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IVISense Hypoxia CA IX 680 Fluorescent Probe (HypoxySense)

IVISense Hypoxia CA IX 680 (HypoxiSense 680) is a carbonic anhydrase IX (CA IX) targeted fluorescent in vivo imaging probe that can be used to image CA IX overexpression in response to hypoxia. Oxygen deprivation is associated with several disease states including angiogenisis, pulmonary disease, inflammation, and cancer.

For research use only. Not for use in diagnostic procedures.

貨號 NEV11070
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詳細信息

In cancer, hypoxia occurs in tumors as a result of the poor ability of their disorganized vascular networks to deliver blood borne oxygen. IVISense Hypoxia CA IX 680 fluorescent imaging probe detects the tumor cell surface expression of carbonic anhydrase 9 (CA IX) protein, which increases in hypoxic regions within many tumors, especially in cervical, colorectal, non-small cell lung tumors. Pairing IVISense Hypoxia CA IX 680 agent with optical fluorescent imaging technology allows you to image and quantitate tumor sub-regions undergoing hypoxia-related changes, non-invasively and in vivo.

規格

熒光劑類型 Targeted
光學成像分類 Fluorescence Imaging
產品品牌名稱 IVISense
包裝量 1.0 Units
運輸條件 藍冰
治療領域 Angiogenesis, Arthritis, Oncology/Cancer
產品尺寸 1 Vial (10 doses)
波長 680 nm
資源
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Ebook

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Researchers trust our in vivo imaging solutions to give them reliable, calibrated data that reveals pathway characterization and therapeutic efficacies for a broad range of indications. Our reagents, instruments, and applications support have helped hundreds of research projects over the years. And ...

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產品手冊

In Vivo Imaging Reagents

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單頁

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HypoxySense 680 (Product Sheet)

Hypoxia occurs in tumors as a result of the poor ability of their disorganized vascular networks to deliver blood borne oxygen. HypoxiSense detects the tumor cell surface expression of carbonic,anhydrase 9 (CA IX) protein, which increases in hypoxic regions,within many tumors, especially in cervical ...

PDF 546 KB

技術說明

HypoxiSense 680 (Protocol)

HypoxiSense 680 in vivo imaging Protocol

PDF 257 KB

指南

IVISense™ Fluorescent Probe Selector Guide for Oncology Research

The goal of in vivo fluorescence molecular imaging is to enable non-invasive visualization and quantification of cellular and biological functioning to better understand and characterize disease processes and treatment effects earlier within the context of a biological system.

This s ...

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白皮書

The Role of In Vivo Imaging in Drug Discovery and Development

The primary goal of preclinical imaging is to improve the odds of clinical success and reduce drug discovery and development time and costs. Advances in non-invasive in vivo imaging techniques have raised the use of animal models in drug discovery and development to a new level by enabling quick ...

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