IVISense™ Renin 680 FAST (ReninSense™) is recognized and activated by rodent forms of renin in preclinical in vivo imaging models. IVISense Renin 680 FAST may be used to monitor abnormal Renin-Angiotensin System (RAS) function, progression of disease, and the efficacy of therapeutic treatment in disorders such as hypertension, cardiovascular disease, as well as some neurological diseases.
For research use only. Not for use in diagnostic procedures.
false false
IVISense Renin 680 FAST™ is a member of a family of activatable fluorescent imaging probes comprising a novel architecture, termed F.A.S.T. (Fluorescent Activatable Sensor Technology), that confers an improved pharmacokinetic profile with a broader range of early imaging timepoints. This architecture also offers higher target specific signal with reduced background.
IVISense Renin 680 FAST is a Renin activatable agent that is optically silent upon injection and produces fluorescent signal after cleavage by renin produced in the kidneys. The Renin-Angiotensin System (RAS) is the hormone system involved in regulating blood pressure and fluid balance in the body.
| 熒光劑類型 | Activatable |
|---|---|
| 光學成像分類 | Fluorescence Imaging |
| 產品品牌名稱 | IVISense |
| 包裝量 | 1.0 Units |
| 運輸條件 | 藍冰 |
| 產品尺寸 | 1 Vial (10 doses) |
| 波長 | 680 nm |
Researchers trust our in vivo imaging solutions to give them reliable, calibrated data that reveals pathway characterization and therapeutic efficacies for a broad range of indications. Our reagents, instruments, and applications support have helped hundreds of research projects over the years. And ...
Our comprehensive range of bioluminescent and fluorescent imaging reagents provide researchers with the necessary tools to better understand early disease-related biological changes, track disease progression, help guide the drug discovery process, and evaluate efficacy and safety of drug candida ...
Fluorescence molecular imaging is the visualization of cellular and biological function in vivo to gain deeper insights into disease processes and treatment effects. Designing an effective study from the beginning can help save time and resources.
Learn about several important best p ...
ReninSense 680 FAST activatable fluorescent imaging agent
The goal of in vivo fluorescence molecular imaging is to enable non-invasive visualization and quantification of cellular and biological functioning to better understand and characterize disease processes and treatment effects earlier within the context of a biological system.
This s ...
The primary goal of preclinical imaging is to improve the odds of clinical success and reduce drug discovery and development time and costs. Advances in non-invasive in vivo imaging techniques have raised the use of animal models in drug discovery and development to a new level by enabling quick ...
