IVISbrite™ Escherichia coli Xen14 bioluminescent bacteria is derived from the parental strain E. coli WS2572, a clinical isolate from Weihenstephan Culture Collection. For in vitro or in vivo imaging applications, IVISbrite E. coli-Xen14 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.
For research use only. Not for use in diagnostic procedures.
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Infectious disease is a perennially important area for both life science research and drug discovery. Some of the first applications of IVIS® imaging technology were in tracking infections and monitoring host responses, and these applications are still at the forefront of research. Our bioluminescent infectious disease light-producing microorganisms have been developed to mimic both acute and chronic standard infection protocols presently used by researchers, e.g., lung, sepsis, meningitis, GI, and biofilm infections.
Advantages of using bioluminescent light-producing microorganisms for drug discovery in vitro:
Advantages of using bioluminescent light-producing microorganisms for drug discovery in vivo:
| Gram Positive Gram Negative | Gram negative |
|---|---|
| Luciferase Classification | Bacterial luciferase |
| Optical Imaging Classification | Bioluminescence Imaging |
| Product Brand Name | IVISbrite |
| Shipping Condition | Ambient |
| Therapeutic Area | Infectious Diseases |
| Unit Size | 1 agar plate |
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