The EnSight® multimode plate reader offers HTS Alpha and Ultra-sensitive Luminescence technologies alongside conventional multimode detection technologies. It can read a 384-well plate in less than 2 mins for all detection technologies. When equipped with a quad monochromator, the EnSight plate reader can improve performance for absorbance and fluorescence detection. In addition, stacker and robotic interface options are available, ideal for automation. The system’s modular design, combined with workflow-based Kaleido™ data acquisition & analysis software, gives a truly versatile plate reader that gets users productive quickly.
An exceptional solution for a wide range of academic and research applications, including metabolomics, proteogenomics, pharmocology, and biomarker discovery, the QSight LC/MS/MS platform delivers the key technologies you count on in a triple quadrupole solution – in a compact, easy-to-use design.
Uncover deep biological understanding in your everyday assays and innovative applications using the Operetta CLS™ high-content analysis system. Featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details. And with our simple, powerful Harmony 4.5 software, Operetta CLS™ lets you find even subtle phenotypic changes.
The EnVision XCite multimode plate reader provides exceptional sensitivity across all detection technologies, while keeping you flexible with monochromator option and full upgradeability.
And, the Enhanced Security software option includes tools to facilitate 21 CFR Part 11 compliance for integration into regulated environments (GxP).
The IVIS® Lumina™ S5 high-throughput 2D optical imaging system combines high-sensitivity bioluminescence and fluorescence in a benchtop format. With an expanded 5 mouse field of view for 2D optical imaging plus our unique line of accessories to accelerate setup and labeling, it has never been easier or faster to get robust data- and answers- on anatomical and molecular aspects of disease.
The Alpha SureFire®Ultra™ Multiplex phospho-eIF2α (Ser51) + Total eIF2α assay kit is used to measure both the phosphorylation (on Ser51) and total levels of endogenous eIF2α in cellular lysates. The assay is an ideal system for the screening of modulators of receptor activation (e.g. agonists and antagonists) as well as agents acting intracellularly, such as small molecule inhibitors of signal transduction. The assay will measure eIF2α phosphorylation by either recombinant or endogenous receptors, and can be applied to primary cells.
The AlphaLISA®SureFire®Ultra™ phospho-BTK (Tyr551) assay kit can be used to measure levels of BTK (phosphorylated at Tyr551) in cellular lysates using no-wash Alpha technology.
The Alpha SureFire®Ultra™ Multiplex p-EGFR (Tyr1068) + Total EGFR assay kit is used to measure both phosphorylated and total levels of EGFR in cellular lysates. The assay is an ideal system for the screening of modulators of receptor activation (e.g. agonists and antagonists) as well as agents acting intracellularly, such as small molecule inhibitors of signal transduction. The assay will measure EGFR (Tyr1068) activation by either recombinant or endogenous receptors, and can be applied to primary cells.
DELFIA® Toolbox kits allow you to build your own DELFIA time-resolved fluorescence (TRF) assay using your preferred antibody against the analyte of interest. Painlessly switch your traditional ELISA to one with a wider dynamic range, higher sensitivity, and great signal stability. This kit contains all necessary reagents to perform a sandwiching immunoassay using DELFIA Europium-labeled streptavidin for detection.
Measure binding of small molecule drug candidates to target protein in a cellular environment with Alpha CETSA® target engagement assays. For use in combination with Pelago Bioscience's CETSA® (Cellular Thermal Shift Assay) technology, this kit provides a convenient no-wash assay for detection and quantitation of small molecule binding to BCL-2, and can be used in hit identification, hit confirmation, and lead optimization studies for increased confidence and better prediction early in the drug discovery process. Please note that a valid CETSA® subscription from Pelago Biosciences is required for use.