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AlphaLISA Binding Kits

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蛋白質相互作用和結合穿插在大量的生物過程中。高效，高靈敏度研究大蛋白質相互作用的檢測需求變得日益重要。Alpha技術作為一種高度靈活，均勻，免洗方法，非常適合測量蛋白質之間相互作用和大小接近200納米的複合物。基於微珠的親近均相測定，Alpha 技術提供了測定許多生物靶標的可能性，包括酶，受體 - 配體相互作用，低親和力相互作用，第二信使水平，DNA，RNA，蛋白質，肽，糖和小分子。

檢測特點及優勢特點：

  • 免洗步驟，無分離步驟
  • 易用性：少量加樣步驟，快速分析開發
  • 廣泛的親和力：檢測強或弱的相互作用，從pM到mM親和力
  • 距離：測量非常大的蛋白質或抗體複合物 - 跨越200nm或更多
  • 高親合力：每個珠子上的多個結合位點能夠使用納摩爾濃度的抗體或蛋白質，以及使用低親和力結合劑

產品與服務 (36)
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1-25 的 36 產品與服務

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    AlphaLISA Human C1q Binding Kit

    AL3169HV , AL3169C , AL3169F

    The AlphaLISA® Human C1q Binding Kit is designed to monitor the binding of the IgG Fc region to the human C1q protein.

  • PROTAC binding assay kit
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    AlphaLISA Human XIAP BIR3 Binding Kit

    AL3173C , AL3173F

    The AlphaLISA® Human XIAP BIR3 Binding Kit is designed to screen and characterize compounds that specifically bind the E3 ligase, XIAP BIR3 domain, using Alpha Technology.

  • PROTAC binding assay kit
    快速瀏覽

    AlphaLISA Human XIAP BIR2 Binding Kit

    AL3172C , AL3172F

    The AlphaLISA® Human XIAP BIR2 Binding Kit is designed to screen and characterize compounds that specifically bind the E3 ligase, XIAP BIR2 domain, using Alpha Technology.

  • AlphaLISA assay technology
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    AlphaLISA Human MDM2 Binding Kit

    AL3168C , AL3168F

    The AlphaLISA® Human MDM2 Binding Kit is designed to screen and characterize compounds that specifically bind the E3 ligase, MDM2, using Alpha Technology.

  • AlphaLISA assay technology
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    AlphaLISA Human cIAP1 BIR3 Binding Kit

    AL3167C , AL3167F

    The AlphaLISA® Human cIAP1 BIR3 Binding Kit is designed to screen and characterize compounds that specifically bind the E3 ligase, cIAP1 BIR3 domain, using Alpha Technology.

  • AlphaLISA assay technology
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    AlphaLISA Human cIAP1 BIR2 Binding Kit

    AL3166C , AL3166F

    The AlphaLISA® Human cIAP1 BIR2 Binding Kit is designed to screen and characterize compounds that specifically bind the E3 ligase, cIAP1 BIR2 domain, using Alpha Technology.

  • PROTAC binding assay kit
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    AlphaLISA Human KRAS G12C/SOS1 Binding Kit

    AL3151C , AL3151F
    The AlphaLISA® Human KRAS G12C/SOS1 Binding Kit is designed for the detection of binding activity between human KRAS G12C and SOS1, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to identify inhibitors of the KRAS G12C / SOS1 protein interaction.
  • PROTAC binding assay kit
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    AlphaLISA Human KRAS WT/SOS1 Binding Kit

    AL3150C , AL3150F
    The AlphaLISA® Human KRAS WT/SOS1 Binding Kit is designed for the detection of binding activity between human KRAS WT and SOS1, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This KRAS SOS1 assay kit can be used to identify inhibitors of KRAS WT / SOS1 protein interactions.
  • PROTAC binding assay kit
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    AlphaLISA Human KRAS G12C GTP Binding Kit

    AL3149C , AL3149F
    The AlphaLISA® Human KRAS G12C GTP Binding Kit is designed for the detection of binding activity between human KRAS G12C mutant and GTP, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to identify KRAS G12C/GTP inhibitors.
  • PROTAC binding assay kit
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    AlphaLISA Human KRAS WT GTP Binding Kit

    AL3148C , AL3148F
    The AlphaLISA® Human KRAS WT GTP Binding Kit is designed for the detection of binding activity between human KRAS wild type (WT) and GTP, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This KRAS GTP assay can be used to identify KRAS WT / GTP inhibitors.
  • PROTAC binding assay kit
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    AlphaLISA Human Cereblon Binding Kit

    AL3147C , AL3147F

    The AlphaLISA® Human Cereblon Binding Kit is designed to screen and characterize compounds that specifically bind the E3 ligase, Cereblon, using Alpha Technology.

  • PROTAC binding assay kit
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    AlphaLISA SARS-CoV2 ACE2/S1 Binding Kit

    AL3146C , AL3146F

    The AlphaLISA® SARS-CoV2 ACE2/S1 Binding Kit is a protein-protein interaction assay for ACE2-Spike inhibitor selection in biochemical format using Alpha Technology.

  • PROTAC binding assay kit
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    STING WT AlphaLISA Binding Kit

    AL3144C , AL3144F
    The AlphaLISA® STING WT Binding Kit is a sandwich immunoassay for quantitative detection of STING WT Binding in cellular lysates using Alpha Technology.
  • AlphaLISA HIV 1 p24 detection kit
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    PD-1/PD-L1 (cyno) AlphaLISA Binding Kit

    AL583C , AL583F

    The AlphaLISA® cyno PD-1/PD-L1 binding kit is designed for the detection of binding activity between cyno PD-1 and PD-L1, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.

  • AlphaLISA Binding
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    PCSK9/LDLR (human) AlphaLISA Binding Kit

    AL3132C , AL3132F

    This kit is designed to assess binding and inhibition of human PCSK9 and LDLR, using a homogeneous AlphaLISA assay (no wash steps). This assay can facilitate the design and development of antibody therapetics using competition assays.

    This is a replacement for AL3119.

  • AlphaLISA HIV 1 p24 detection kit
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    CD28/CD86 (human) AlphaLISA Binding Kit

    AL3131C , AL3131F

    The AlphaLISA® human CD28/CD86 binding kit is designed for the detection of binding activity between human CD28 and CD86, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.

  • AlphaLISA HIV 1 p24 detection kit
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    PD-1/PD-L2 (human) AlphaLISA Binding Kit

    AL3128C , AL3128F
    The AlphaLISA® human PD-1/PD-L2 binding kit is designed for the detection of binding activity between human PD-1 and PD-L2, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.
  • AlphaLISA Binding
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    TNFα/TNFR2 (human) AlphaLISA Binding Kit

    AL3121C , AL3121F
    The AlphaLISA® human TNFα/TNFR2 binding kit is designed for the detection of binding activity between human TNFα and TNFR2, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.
  • AlphaLISA Binding
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    TNFα/TNFR1 (human) AlphaLISA Binding Kit

    AL3120C , AL3120F
    The AlphaLISA® human TNFα/TNFR1 binding kit is designed for the detection of binding activity between human TNFα and TNFR1, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.
  • AlphaLISA Binding
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    4-1BB/4-1BBL (human) AlphaLISA Binding Kit

    AL3113C , AL3113F
    The AlphaLISA® 4-1BB/4-1BBL binding kit is designed for the detection of binding activity between human 4-1BB and 4-1BBL, using a fast and simple homogeneous AlphaLISA assay (no wash steps). This assay can be used to screen for small molecules that inhibit binding, as a competitive ligand binding (CLB) assay to screen therapeutic blocking antibodies, and for potency assays.
  • AlphaLISA HIV 1 p24 detection kit
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    FcRn (human) AlphaLISA Binding Kit

    AL3095C , AL3095F
    The AlphaLISA human FcRn binding kit is designed for the detection of binding between FcRn and human IgG using a homogeneous AlphaLISA assay (no wash steps). This assay can facilitate the design and development of antibody therapeutics using a competition assay format.
  • AlphaLISA HIV 1 p24 detection kit
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    FcγR3B (CD16b) AlphaLISA Binding Kit

    AL3094C , AL3094F
    The AlphaLISA FCGR3B (CD16b) binding kit is designed for the detection of binding between FcγR3B (CD16b) and human IgG Fc fragment using a homogeneous AlphaLISA assay (no wash steps). This assay can facilitate the design and development of antibody therapeutics using a competition assay format.
  • AlphaLISA Binding
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    PD-1/PD-L1 (mouse) AlphaLISA Binding Kit

    AL580C , AL580F
    AlphaLISA®小鼠PD-1/PD-L1結合技術可以在體外和體內研究中，幫助構建和表征小分子和大分子抗小鼠PD-1/PD-L1試劑。該試驗也可以測試其他可能的結合配體，例如PD-L2，或表征配體亞區阻礙結合的能力。並且，AlphaLISA®可以通過均相化試驗，測定抗人PD-1/PD-L1試劑的小鼠交叉反應性。（無洗脫步驟）
  • AlphaLISA HIV 1 p24 detection kit
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    FcγR2A/CD32a (167R) AlphaLISA Binding Kit

    AL3087C , AL3087F
    This kit is designed for the detection of binding between FCGR2A (CD32a) (167R) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapeutics by using competitive binding.
  • AlphaLISA HIV 1 p24 detection kit
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    FcγR2A/CD32a (167H) AlphaLISA Binding Kit

    AL3086C , AL3086F
    This kit is designed for the detection of binding between FCGR2A (CD32a) (167H) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapeutics by using competitive binding.
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