Track cancer growth and metastases or gain a better understanding of cancer biology using IVISbrite™ (formerly Bioware Brite) bioluminescent tumor cell lines.
Our bioluminescent tumor cell lines are labeled with red-shifted luciferase (Red F-luc) or dual labeled with luciferase and fluorescent reporters (GFP). These red-shifted tumor cell lines are significantly brighter (10-20 fold brighter in vitro) than other firefly luciferases. IVISbrite oncology cell lines are bright enough to measure tumor growth in your in vivo optical imaging system right after injection, much earlier than when tumors are palpable, allowing you to start collecting data at time points impossible with traditional micrometer measurements. Available tumor cell lines cover a range of cancer models including breast, colorectal, prostate, lung, lymphoma and many more.
All IVISbrite bioluminescent oncology cell lines meet the highest quality standards and are confirmed pathogen-free.
| Source | Cell line labeled with Red F-luc | Cell Type | Species |
|---|---|---|---|
| Brain | U-87 MG GL261 |
Glioblastoma Glioma |
Human Murine |
| Breast | 4T1 MCF-7 |
Breast mammary adenocarcinoma Breast mammary adenocarcinoma |
Murine Human |
| Colorectal | HCT-116 HT-29 Colo205 |
Colorectal carcinoma Colorectal carcinoma Colorectal adenocarcinoma |
Human Human Human |
| Fibrosarcoma | HT1080 | Fibrosarcoma | Human |
| Hepatic | HepG2 | Hepatic carcinoma | Human |
| Blood | K-562 | Leukemia, Chronic Myelogenous Leukemia | Human |
| Lung | A549 LL/2 NCI-H460 |
Lung carcinoma Lung carcinoma Lung adenocarcinoma |
Human Murine Human |
| Ovarian | SKOV3 | Ovarian adenocarcinoma | Human |
| Pancreatic | BxPC3 | Pancreatic adenocarcinoma | Human |
| Prostate | PC-3 LnCaP |
Prostate adenocarcinoma Prostate, supraclavicular lymph node carcinoma |
Human Human |
| Skin | B16-F10 | Skin melanoma | Murine |
For research use only. Not for use in diagnostic procedures.
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The IVISbrite™ U87 MG Red F-luc tumor cell line (Bioware® Brite U87MG-Red-FLuc) is a light-producing cell line derived from U87 MG-human brain glioblastoma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc), for a brighter, red-shifted signal.
For research use only. Not for use in diagnostic procedures.
The IVISbrite™ SKOV3 Red F-luc tumor cell line (Bioware® Brite SKOV3-Red-FLuc) is a light-producing cell line derived from SKOV3 human ovarian adenocarcinoma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc), for a brighter, red-shifted signal.
For research use only. Not for use in diagnostic procedures.
The IVISbrite™ PC3 Red-F-luc-GFP tumor cell line (Bioware® Brite PC3-Red-FLuc-GFP) is a light-producing and fluorescent cell line derived from PC3 human prostate adenocarcinoma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc) fused to GFP (Green Fluorescent Protein), for a brighter, red-shifted bioluminescent or green fluorescent signal.
For research use only. Not for use in diagnostic procedures.
The IVISbrite™ PC3 Red-F-luc tumor cell line (Bioware® Brite PC3-Red-FLuc) is a light-producing cell line derived from PC3 human prostate adenocarcinoma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc), for a brighter, red-shifted signal.
For research use only. Not for use in diagnostic procedures.
The IVISbrite™ NCI-H460 Red F-luc tumor cell line (Bioware® Brite NCI-H460-Red-FLuc) is a light-producing cell line derived from NCI-H460 human lung adenocarcinoma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc), for a brighter, red-shifted signal.
For research use only. Not for use in diagnostic procedures.
The IVISbrite™ MCF7 Red F-luc tumor cell line (Bioware® Brite MCF7-Red-FLuc) is a light-producing cell line derived from MCF7-human mammary adenocarcinoma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc), for a brighter, red-shifted signal.
For research use only. Not for use in diagnostic procedures.
The IVISbrite™ LNCaP Red F-luc tumor cell line (Bioware® Brite LNCaP-Red-FLuc) is a light-producing cell line derived from LNCaP human prostate carcinoma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc), for a brighter, red-shifted signal.
For research use only. Not for use in diagnostic procedures.
The IVISbrite™ LL/2 Red F-luc tumor cell line (Bioware® Brite LL/2-Red-FLuc) is a light-producing cell line derived from a mouse lung carcinoma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc), for a brighter, red-shifted signal.
For research use only. Not for use in diagnostic procedures.
The IVISbrite™ K562 Red F-luc tumor cell line ( Bioware® Brite K562-Red-FLuc) is a light-producing cell line derived from K562-human chronic myelogenous leukemia (CML). The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc), for a brighter, red-shifted signal.
For research use only. Not for use in diagnostic procedures.
The IVISbrite™ HT1080 Red F-luc tumor cell line (Bioware® Brite HT1080-Red-FLuc) is a light-producing cell line derived from HT1080 human fibrosarcoma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc), for a brighter, red-shifted signal.
For research use only. Not for use in diagnostic procedures.
The IVISbrite™ HT29 Red F-luc tumor cell line (Bioware® Brite HT-29-Red-FLuc) is a light-producing cell line derived from HT29-human colorectal adenocarcinoma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc), for a brighter, red-shifted signal.
For research use only. Not for use in diagnostic procedures
The IVISbrite™ HepG2 Red F-luc tumor cell line (Bioware® Brite HepG2-Red-FLuc) is a light-producing cell line derived from HepG2 human hepatocellular carcinoma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc), for a brighter, red-shifted signal.
For research use only. Not for use in diagnostic procedures.
The IVISbrite™ HCT116 Red F-luc tumor cell line (Bioware® Brite HCT-116-Red-FLuc) is a light-producing cell line derived from HCT116 human colorectal carcinoma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc), for a brighter, red-shifted signal.
For research use only. Not for use in diagnostic procedures..
The IVISbrite™ GL261 Red F-luc tumor cell line (Bioware® Brite GL261-Red-FLuc) is a light-producing cell line derived from GL261 mouse glioma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc), for a brighter, red-shifted signal.
For research use only. Not for use in diagnostic procedures.
The IVISbrite™ Colo205 Red F-luc tumor cell line (Bioware® Brite Colo205-Red-FLuc) is a light-producing cell line derived from Colo205-human colorectal adenocarcinoma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc), for a brighter, red-shifted signal.
For research use only. Not for use in diagnostic procedures.
The IVISbrite™ BxPC3 Red F-luc tumor cell line (Bioware® Brite BxPC3-Red-FLuc) is a light-producing cell line derived from BxPC3 human pancreatic adenocarcinoma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc), for a brighter, red-shifted signal.
For research use only. Not for use in diagnostic procedures.
The IVISbrite™ B16F10 Red F-luc tumor cell line (Bioware® Brite B16F10-Red-FLuc) is a light-producing cell line derived from B16F10 mouse melanoma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc), for a brighter, red-shifted signal.
For research use only. Not for use in diagnostic procedures.
The IVISbrite™ A549 Red F-luc tumor cell line (Bioware® Brite A549-Red-Fluc) is derived from A549-human lung carcinoma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-Luc), for a brighter, red-shifted signal.
For research use only. Not for use in diagnostic procedures.
The IVISbrite™ 4T1 Red F-luc-GFP tumor cell line (Bioware® Brite 4T1-Red-FLuc-GFP) is a light-producing and fluorescent cell line derived from 4T1 mouse mammary gland adenocarcinoma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc) fused to GFP (Green Fluorescent Protein), for a brighter, red-shifted bioluminescent or green fluorescent signal.
For research use only. Not for use in diagnostic procedures.
The IVISbrite™ 4T1 Red F-luc tumor cell line (Bioware® Brite 4T1-Red-FLuc) is a light-producing cell line derived from 4T1 mouse mammary gland adenocarcinoma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc), for a brighter, red-shifted signal.
For research use only. Not for use in diagnostic procedures.
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