Introducing Revvity - Expanding the boundaries of human potential through science
(Revvity was previously affiliated with 爱游戏平台注册登录
, Inc.)
We are now two standalone organizations
Life Sciences & Diagnostics and Analytical & Enterprise Solutions
Functional genomic screens enable the modulation of hundreds or thousands of genes in a single experiment to identify genetic pathways, cellular processes, novel therapeutic targets, and to genetically profile existing or potential therapeutics.
爱游戏平台注册登录 ’s wide range of CRISPR solutions are designed to support you in every step of your CRISPR workflow. From CRISPR and RNAi libraries for high-throughput functional genomic screening to automated image platforms and cellular assays, we offer all the tools and technologies to help you edit with confidence and maximize your chance of success.
CRISPR has exploded within the scientific research community and contributed to many notable breakthroughs. With a ride range of important applications, the technology has become pivotal for research and beyond.
Enables loss of function studies: screening with complete loss of gene expression provides the maximal window for phenotypic effect and high statistical power for hit discovery.
This homology-directed repair (HDR) introducing or correcting a SNP mutation, or adding a reporter tag to an endogenous gene.
Represses expression rather than completely knocking out the target gene and is ideally suited to study drugability and to evaluate the function of genes that when knocked-out are essential or that are amplified.
Amplifies gene expression in its endogenous context and enables for the first time, to study activation-linked responses on a genome-wide level.
Selecting the appropriate format of CRISPR reagents is the first critical step before starting a screen. We offer a variety of formats, so that regardless of the scientific question, we can support your experimental needs.
Cas9 nuclease reagents are available as Cas9 protein, mRNA, plasmid, or lentiviral Cas9. For optimization and enrichment, versions co-expressing a fluorescent tag are available.
Edit-R ™ CRISPR guide RNA are available in pools or as individual reagents, as predefined CRISPR knockout libraries, or a library can be designed using the cherry-pick library tool.
HDR relies on the presence of a donor template with sufficient homology to the regions flanking the cut site. The homology arms’ length and donor type will depend on the modification being made. Our templates make it easy to customize a donor oligo.
Successful introduction of gRNA and Cas9 protein into the cell is key to any gene-editing experiment to ensure efficiency. Our range of transfection reagents provide efficient and reliable delivery of CRISPR gRNA with minimal cellular toxicity.
These types of assays are often labor intensive and require many steps for re-suspending the CRISPR reagents, cell transfer, and treatment addition or staining. To accelerate your assay, we offer a full range of liquid handling, integrated laboratory automation, and cell counters that together with our specially designed microplates, improve your workflow and provide consistent and quality results.
For research use only. Not for use in diagnostic procedures.
The JANUS® G3 automated liquid handling workstations offer flexible automated sample preparation solutions to meet your specific application needs. The JANUS G3 portfolio includes both dedicated, application-specific workstations and personalized automated solutions. The JANUS G3 workstation can be ...
From cellular screening and imaging applications to high-throughput screening and genomics-based applications, custom explorer™ G3 integrated workstations provide innovative application-focused laboratory automation solutions which simplify microplate handling, liquid handling, and detection. With c ...
Choosing the right microplate is a critical, often overlooked, part of an assay. The right microplate helps provides valuable data, whereas the wrong microplate can lead to missed or inaccurate data leading to missed project timelines and ultimately higher costs. New technologies for drug developmen ...
Nexcelom offers a broad range of slide or plate-based automated cell counters featuring brightfield and fluorescent read-out capabilities.
Once it's time to acquire an image, options for read-outs can range from simple phenotypic or viability assays to multiparametric high-content analysis. Our line of sensitive yet powerful microplate readers, live cell imagers, and high-content analysis systems, plus innovative reagents enable you to accelerate your workflow and reduce costs.
爱游戏平台注册登录 's PhenoVue™ suite of cellular imaging reagents – including cell painting kits, organelle and cell compartment stains, fluorescent-labeled secondary antibodies, and cell function reagents – complements our proven high-content screening instruments and image analysis software. Cellular ima ...
High-Content Analysis (HCA) or High-Content Screening (HCS) combines high-throughput automated imaging and analysis to extract quantitative multi-parametric data at the single-cell level. Originally developed as a complementary technology to traditional biochemical high-throughput screening (HTS) in ...
As many of you know, microplate readers are instruments used to detect biological, chemical, biochemical or physical events from samples in a microplate. This is where it all starts for your basic research, assay development and therapeutic research. A powerful and reliable plate reader is what you ...
Drug discovery starts with an understanding of the basics of diseases and disease pathways. Throughout the process of unraveling the complexity of disease pathways, identifying and characterizing targets, high throughput screening, and lead optimization 爱游戏平台注册登录 has the assays you can count on. P ...
The Celigo image cytometry system provides high-throughput, whole-well imaging and quantitative data through image analysis in bright field and up to four fluorescent channels, for a wide variety of cell-based assays.
Nexcelom Bioscience offers a wide range of fluorescent reagents and kits for cell counting and cell-based assays. Our reagents are optimized to work with Cellometer and Celigo imaging systems as well as other fluorescence-based instruments.
Once your gene-editing experiment is complete, you’re faced with readouts and large amounts of data that need to be analyzed. Our next generation informatics solutions help you to contextually analyze all that data, so you have more physiologically relevant results to make more informed decisions.
Signals Image Artist™ is our next generation image analysis and management platform for high-content screening and cell imaging data. Quickly process, analyze, share, and store the vast volumes of data generated by high-content screening and cellular imaging, including live cell imaging, 3D imaging, ...
Signals VitroVivo is an intuitive, configurable, flexible screening workflow processor coupled with the unparalleled data visualization and analysis capabilities of TIBCO Spotfire.
Disease Models