Iodinated Compounds

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Radiometric detection is considered the gold standard for many applications, from drug discovery and development to plant sciences. ¹²⁵I labeled compounds are useful in both basic research and drug discovery where they are used as tracers in radioimmunoassays (RIA) and ligands in binding studies. ¹²⁵I is particularly versatile as it emits both gamma and Auger electrons. This means that can be it counted either directly, without requiring scintillation, or by using a liquid scintillation counter. We offer a wide range of ¹²⁵I labeled compounds as well as customized services to label your unique compound.

For Research and investigative use only.

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Drug Discovery & Development (52)

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Angiogenesis (6)
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CNS & Neurologic (27)
Diabetes (5)
Gastrointestinal (8)
Inflammation (15)
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Product Brand Name

NEN Radiolabeled Ligands (52)

Detection Method

Radiometric (54)

Receptor Type

Adenosine (1)
Adrenoceptors (2)
Angiotensin (3)
Apelin (1)
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Calcium (2)
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Neurotensin (1)
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Oxytocin (1)
Platelet-Derived Growth Factor (1)
Potassium (1)
Somatostatin (1)
Thyroid Hormone (3)
Vasoactive Intestinal Peptide (2)
Vasopressin (2)

Radionuclide

¹²⁵I (54)

Label Position

Nominally Labeled (53)
Specifically Labeled (1)

Concentration

1.0 - 10 mCi/mL (1)
1.12 mCi/mL (1)
1.14 mCi/mL (1)
152 µCi/mL (1)
170.1 µCi/mL (1)
171 µCi/mL (1)
172.5 µCi/mL (1)
182 µCi/mL (1)
236 µCi (1)
3.06 MBq/mL (1)
345 µCi/mL (3)
353 µCi/mL (1)
45.7 µCi/mL (1)
6.05 MBq/mL (1)
79.2 µCi/mL (2)
83.8 µCi/mL (1)
85.1 µCi/mL (1)
87.4 µCi/mL (1)
87.6 µCi/mL (1)
87.9 µCi/mL (1)
88.5 µCi/mL (1)
<1.0 µCi/mL (3)
<100 µCi/mL (1)

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1-25 of 54 Products & Services

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Vasopressin, [¹²⁵I]Tyr², Arg⁸

NEX128010UC , NEX128050UC

Vasopressin, labeled with ¹²⁵I on tyrosine residue 2. Vasopressin binds and activates vasopressin receptors, a group of GPCRs that are potential drug targets for hyponatremia, congestive heart failure, and cirrhosis.

Price Range : 1492.00 USD - 3514.00 USD
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Vasopressin (Linear), V-1A Antagonist (Phenylacetyl1, 0-Me-D-Tyr2, [¹²⁵I-Arg6]-)

NEX310010UC , NEX310050UC

Vasopressin (linear), labeled with ¹²⁵I. Linear vasopressin acts as an antagonist at vasopressin receptor 1A (V1AR).

Price Range : 1578.00 USD - 3752.00 USD
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Vasoactive Intestinal Polypeptide (human, porcine, rat), [¹²⁵I]

NEX192010UC , NEX192050UC

Vasoactive intestinal polypeptide (VIP), labeled with ¹²⁵I. VIP binds vasoactive intestinal peptide receptors VPAC₁ and VPAC₂, a group of GPCRs that are potential drug targets for nervous and endocrine disorders and several types of cancer.

Price Range : 1570.00 USD - 3827.00 USD
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Somatostatin, [¹²⁵I]Tyr¹¹

NEX389010UC , NEX389050UC

Somatostatin, labeled with ¹²⁵I. Somatostatin binds somatostatin receptors, and inhibits the secretion of insulin and glucagon.

Price Range : 1478.00 USD - 3446.00 USD
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Triiodothyronine, ([¹²⁵I]-T₃)

NEX110100UC , NEX110250UC , NEX110500UC , NEX110H100UC , NEX110H250UC , NEX110H500UC , NEX110X100UC , NEX110X250UC , NEX110X500UC

Triiodothyronine (T₃) labeled with ¹²⁵I. Triiodothyronine is a thyroid hormone that affects growth and development, body temperature, and heart rate. T₃ detection by radioimmunoassay is a common test of thyroid gland function. This product is offered at three specific activities. Specific activity indicates how much radioactivity there is per molecule of ligand. Several of our ¹²⁵I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one ¹²⁵I labeling site is available, 4400 Ci/mmol if two labeling sites are available).

Price Range : 1216.00 USD - 4111.00 USD
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Thyroxine, ([¹²⁵I]-T4), 5700 µCi/µg

NEX111X100UC , NEX111X500UC

Thyroxine (T₄) labeled with ¹²⁵I. Thyroxine is a thyroid hormone that is responsible for regulation or metabolism. T₄ detection by radioimmunoassay is a common test of thyroid disease. This product is offered at three specific activities. Specific activity indicates how much radioactivity there is per molecule of thyroxine. Several of our ¹²⁵I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one ¹²⁵I labeling site is available, 4400 Ci/mmol if two labeling sites are available).

Price Range : 1475.00 USD - 4332.00 USD
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Thyroxine, ([¹²⁵I]-T4), Specific Activity: 1080-1320 µCi/µg

NEX111H100UC , NEX111H250UC , NEX111H500UC

Thyroxine (T₄) labeled with ¹²⁵I. Thyroxine is a thyroid hormone that is responsible for regulation or metabolism. T₄ detection by radioimmunoassay is a common test of thyroid disease. This product is offered at three specific activities. Specific activity indicates how much radioactivity there is per molecule of thyroxine. Several of our ¹²⁵I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one ¹²⁵I labeling site is available, 4400 Ci/mmol if two labeling sites are available).

Price Range : 1264.00 USD - 4406.00 USD
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Thyroxine, ([¹²⁵I]-T4), Specific Activity: 135-165 µCi/µg

NEX111100UC , NEX111250UC , NEX111500UC

Thyroxine (T₄) labeled with ¹²⁵I. Thyroxine is a thyroid hormone that is responsible for regulation or metabolism. T₄ detection by radioimmunoassay is a common test of thyroid disease. This product is offered at three specific activities. Specific activity indicates how much radioactivity there is per molecule of thyroxine. Several of our ¹²⁵I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one ¹²⁵I labeling site is available, 4400 Ci/mmol if two labeling sites are available).

Price Range : 1440.00 USD - 5700.00 USD
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SDF-1α (human, recombinant), [¹²⁵I]

NEX346005UC , NEX346025UC

Stromal cell-derived factor 1 alpha (SDF-1α; CXCL12), labeled with ¹²⁵I. SDF-1α binds the CXCR4 receptor.

Price Range : 1322.00 USD - 7200.00 USD
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Sauvagine, [¹²⁵I]-Tyr⁰]

NEX306010UC , NEX306050UC

Sauvagine, labeled with ¹²⁵I on the tyrosine 0 residue. Sauvagine is a neuropeptide that acts as an agonist at corticotropin-releasing factor receptors (CRF receptors) 1 and 2.

Price Range : 1704.00 USD - 6600.00 USD
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RTI-55, [¹²⁵I]

NEX272025UC , NEX272250UC

RTI-55, labeled with ¹²⁵I. RTI-55 is a nonselective dopamine reuptake inhibitor that is used to assess neuron degradation in Parkinson's disease and other neurodegenerative diseases.

Price Range : 1478.00 USD - 5200.00 USD
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Peptide YY (Human), ([¹²⁵I]-PYY)

NEX341010UC , NEX341050UC

Peptide YY, labeled with ¹²⁵I. Peptide YY acts as a neuropeptide Y receptor Y2 agonist, is released in response to feeding, and is associated with appetite saiety.

Price Range : 1459.00 USD - 6500.00 USD
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PDGF [¹²⁵I] (human)

NEX433005UC , NEX433025UC

NEX433 [¹²⁵I]-PDGF BB homodimer has been shown to work in RIA and receptor studies, using CHO cell line transfected with human PDGF B receptor, and human artery smooth muscle cells.

Price Range : 1876.00 USD - 7100.00 USD
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Pancreatic Polypeptide (human), [¹²⁵I]

NEX315010UC , NEX315050UC

Human pancreatic polypeptide (PP), labeled with ¹²⁵I. Pancreatic polypeptide acts as an agonist at Pancreatic polypeptide receptors (Neuropeptide Y receptors), a class of GPCRs involved in appetite, circadian rhythm, and anxiety.

Price Range : 1651.00 USD - 5700.00 USD
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PACAP27, [¹²⁵I]

NEX294005UC , NEX294025UC

Pituitary adenylate cyclase activating peptide-27 (PACAP-27), labeled with ¹²⁵I. PACAP-27 binds the pituitary adenylate cyclase-activating polypeptide type I receptor (PAC₁) and vasoactive intestinal peptide receptors (VPAC₁ and VPAC₂).

Price Range : 1304.00 USD - 4470.00 USD
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Ornithine Vasotocin Analog, [¹²⁵I]-OVTA)

NEX254010UC , NEX254050UC

Ornithine Vasotocin Analog (OVTA), labeled with ¹²⁵I. OVTA binds oxytocin receptors, a hormone receptor involved in pregnancy, milk production, stress, social memory, and bonding.

Price Range : 1879.00 USD - 4384.00 USD
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Orexin A, [¹²⁵I]

NEX367010UC , NEX367050UC

Orexin A, labeled with ¹²⁵I. Orexin A binds to orexin receptors (OX₁ and OX₂), which are potential drug targets for sleep disorders.

Price Range : 1868.00 USD - 5800.00 USD
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Ω-Conotoxin MVIIC, [¹²⁵I]

NEX323010UC , NEX323050UC

Ω-Conotoxin MVIIC (ω-Conotoxin MVIIC), labeled with ¹²⁵I. Ω-Conotoxin MVIIC is a neurotoxin that blocks calcium channels.

Price Range : 1215.00 USD - 4641.00 USD
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Ω-Conotoxin GVIA, [¹²⁵I] Tyr²²

NEX239010UC , NEX239050UC

Ω-Conotoxin GVIA (ω-Conotoxin GVIA), labeled with ¹²⁵I on tyrosine residue 22. Omega conotoxin CVIA is a calcium channel blocker.

Price Range : 1021.00 USD - 4310.00 USD
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Neurotensin, [¹²⁵I]Tyr³

NEX198010UC , NEX198050UC

Neurotensin, labeled with ¹²⁵I on the tyrosine 3 residue. Neurotensin functions as an agonist at neurotensin receptors. It is known to induce analgesia, hypothermia and increased locomotor activity. Neurotensin is also involved in the regulation of dopamine.

Price Range : 1644.00 USD - 5200.00 USD
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MIP-1α (human, recombinant), [¹²⁵I]

NEX298005UC , NEX298025UC

Human recombinant macrophage inflammatory protein 1-alpha (MIP-1α; CCL3), labeled with ¹²⁵I. MIP-1α is a cytokine involved in acute inflammation, and binds C-C chemokine receptors CCR1, CCR4, and CCR5.

Price Range : 1202.00 USD - 4928.00 USD
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Iodo-Melatonin, 2-[¹²⁵I]

NEX236050UC , NEX236100UC , NEX236250UC

Melatonin, labeled with ¹²⁵I. Melatonin binds and activates melatonin receptors, a class of GPCRs that are potential drug targets for circadian rhythm sleep disorders and depression.

Price Range : 1715.00 USD - 4084.00 USD
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MCP-1,[¹²⁵I]- labeled, Bolton-Hunter Labeled

NEX332005UC , NEX332025UC

Monocyte chemoattractant protein 1 (MCP-1; CCL2), labeled with ¹²⁵I. MCP-1 is a cytokine released by tumor cells that binds chemokine receptor 2 (CCR2).

Price Range : 1200.00 USD - 5700.00 USD
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Iodoaminopotentidine, [¹²⁵I]

NEX431010UC , NEX431025UC

NEX431 [¹²⁵I]-Aminopotentidine has been shown to work in receptor binding and autoradiography and is an antagonist for histamine (H2) receptors.

Price Range : 1554.00 USD - 3878.00 USD
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Insulin-like Growth Factor-I (human, recombinant), ¹²⁵I

NEX241005UC , NEX241025UC

Insulin-like growth factor 1 (IGF-1), labeled with ¹²⁵I. IGF-1 acts as an agonist at the IGF-1 receptor, a receptor tyrosine kinase, that plays a role in growth, cancer, and aging. IGF-1 also binds the insulin receptor (IR), another receptor tyrosine kinase involved in glucose homeostasis, diabetes, and cancer.

Price Range : 1111.00 USD - 5100.00 USD

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GPCRs: The Pathway to Discovery

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Publication Review
Deciphering the Properties of Neuronal Nicotinic Acetylcholine Receptors Using Radiolabeled α-Bungarotoxin

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