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MacroSep® BIO-Gold PFP exhibits the strongest π-π interaction of all the BIO-Gold phases. Notably in the separation of closely related compounds such as natural compounds and their metabolites in biological matrices, where separation is often difficult or not possible at all on C18 phases. The alternative retention mechanism PFP phases exhibit are therefore increasingly important for method development in bio-pharmaceuticals and the analysis of natural compounds. The most hydrophilic of the BIO-Gold phenyl phases and may be used for fluorine modified biologics based upon a fluorophilicity interaction. Fluorinated phases such as pentafluorophenyl (PFP) with the highest π-π interaction of any the MacroSep BIO series stationary phases are of great importance in HPLC because their selectivity is orthogonal to the selectivity of traditional alkyl phases (C18, C8, C4 etc.). In addition, it may be useful for fluorine modified biologics based upon a fluorophilicity interaction. Notably in the separation of closely related compounds such as natural compounds and their metabolites in biological matrices, where separation is often difficult or not possible at all on C18 phases. The alternative retention mechanism PFP phases exhibit are therefore increasingly important for method development in bio-pharmaceuticals and the analysis of natural compounds.
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The 10 mm guard cartridge holder provides protection against compounds that irreversibly absorb onto the stationary phase. It also provides the ultimate in column protection with a selectable filter frit for elimination of particulates along with a guard cartridge packed with a selectable stationary phase to protection against compounds that irreversibly absorb onto the stationary phase.
MacroSep® BIO-Gold PFP exhibits the strongest π-π interaction of all the BIO-Gold phases. The most hydrophilic of the BIO-Gold phenyl phases and may be used for fluorine modified biologics based upon a fluorophilicity interaction. Fluorinated phases such as pentafluorophenyl (PFP) with the highest π-π interaction of any the MacroSep BIO series stationary phases are of great importance in HPLC because their selectivity is orthogonal to the selectivity of traditional alkyl phases (C18, C8, C4 etc.). In addition, it may be useful for fluorine modified biologics based upon a fluorophilicity interaction.
MacroSep® BIO-Gold PFP exhibits the strongest π-π interaction of all the BIO-Gold phases. The most hydrophilic of the BIO-Gold phenyl phases and may be used for fluorine modified biologics based upon a fluorophilicity interaction. Fluorinated phases such as pentafluorophenyl (PFP) with the highest π-π interaction of any the MacroSep BIO series stationary phases are of great importance in HPLC because their selectivity is orthogonal to the selectivity of traditional alkyl phases (C18, C8, C4 etc.). In addition, it may be useful for fluorine modified biologics based upon a fluorophilicity interaction.
MacroSep® BIO-Gold PFP exhibits the strongest π-π interaction of all the BIO-Gold phases. The most hydrophilic of the BIO-Gold phenyl phases and may be used for fluorine modified biologics based upon a fluorophilicity interaction. Fluorinated phases such as pentafluorophenyl (PFP) with the highest π-π interaction of any the MacroSep BIO series stationary phases are of great importance in HPLC because their selectivity is orthogonal to the selectivity of traditional alkyl phases (C18, C8, C4 etc.). In addition, it may be useful for fluorine modified biologics based upon a fluorophilicity interaction.
MacroSep® BIO-Gold PFP exhibits the strongest π-π interaction of all the BIO-Gold phases. The most hydrophilic of the BIO-Gold phenyl phases and may be used for fluorine modified biologics based upon a fluorophilicity interaction. Fluorinated phases such as pentafluorophenyl (PFP) with the highest π-π interaction of any the MacroSep BIO series stationary phases are of great importance in HPLC because their selectivity is orthogonal to the selectivity of traditional alkyl phases (C18, C8, C4 etc.). In addition, it may be useful for fluorine modified biologics based upon a fluorophilicity interaction.
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