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Life Sciences & Diagnostics and Analytical & Enterprise Solutions
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The AlphaLISA® SureFire® Ultra™ Phospho-RSK1 (Ser380) assay is a sandwich immunoassay for quantitative detection of Phospho-RSK1 (Ser380) in cellular lysates using Alpha Technology.
The AlphaLISA® SureFire® Ultra™ Phospho-RSK1 (Tyr573) assay is a sandwich immunoassay for quantitative detection of phospho RSK1 (Tyr573) in cellular lysates using Alpha Technology.
The AlphaLISA® SARS-CoV2 Spike S1 assay is a sandwich immunoassay for quantitative detection of total SARS-CoV2 Spike S1 in cellular lysates using Alpha Technology.
Alpha Donor beads conjugated to anti-6XHis antibody. This bead can be used to capture 6XHis-tagged proteins for Alpha no-wash protein-protein interaction assays and other applications.
The AlphaLISA® Human Cereblon Detection Kit is designed for detection and quantitation of human cereblon in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
The AlphaLISA® SureFire® Ultra™ Multiplex phospho-STAT1 (Tyr701) + Total STAT1 assay kit is used to measure both the phosphorylation of STAT1 and total levels of endogenous STAT1 in cellular lysates. The assay is an ideal system for the screening of modulators of receptor activation (e.g. agonists and antagonists) as well as agents acting intracellularly, such as small molecule inhibitors of signal transduction. The assay will measure STAT1 phosphorylation by either recombinant or endogenous receptors and can be applied to primary cells.
The AlphaLISA® SureFire® Ultra™ Multiplex phospho-STAT1 (Ser727) + Total STAT1 assay kit is used to measure both the phosphorylation of STAT1 and total levels of endogenous STAT1 in cellular lysates. The assay is an ideal system for the screening of modulators of receptor activation (e.g. agonists and antagonists) as well as agents acting intracellularly, such as small molecule inhibitors of signal transduction. The assay will measure STAT1 phosphorylation by either recombinant or endogenous receptors and can be applied to primary cells.
The AlphaLISA® SureFire® Ultra™ Multiplex phospho-ribosomal protein S6 (Ser240/244) + Total ribosomal protein S6 assay kit is used to measure both the phosphorylation of ribosomal protein S6 and total levels of endogenous ribosomal protein S6 in cellular lysates. The assay is an ideal system for the screening of modulators of receptor activation (e.g. agonists and antagonists) as well as agents acting intracellularly, such as small molecule inhibitors of signal transduction. The assay will measure S6 ribosomal protein phosphorylation by either recombinant or endogenous receptors and can be applied to primary cells.
The AlphaLISA® SureFire® Ultra™ Multiplex phospho-ribosomal protein S6 (Ser235/236) + Total ribosomal protein S6 assay kit is used to measure both the phosphorylation of ribosomal protein S6 and total levels of endogenous ribosomal protein S6 in cellular lysates. The assay is an ideal system for the screening of modulators of receptor activation (e.g. agonists and antagonists) as well as agents acting intracellularly, such as small molecule inhibitors of signal transduction. The assay will measure S6 ribosomal protein phosphorylation by either recombinant or endogenous receptors and can be applied to primary cells.
The AlphaLISA® SureFire® Ultra™ Multiplex phospho-Rb (Thr821/826) + Total Rb assay kit is used to measure both the phosphorylation of Rb and total levels of endogenous Rb in cellular lysates. The assay is an ideal system for the screening of modulators of receptor activation (e.g. agonists and antagonists) as well as agents acting intracellularly, such as small molecule inhibitors of signal transduction. The assay will measure Rb phosphorylation by either recombinant or endogenous receptors and can be applied to primary cells.
The AlphaLISA® SureFire® Ultra™ Multiplex phospho-Rb (Ser807/811) + Total Rb assay kit is used to measure both the phosphorylation of Rb and total levels of endogenous Rb in cellular lysates. The assay is an ideal system for the screening of modulators of receptor activation (e.g. agonists and antagonists) as well as agents acting intracellularly, such as small molecule inhibitors of signal transduction. The assay will measure Rb phosphorylation by either recombinant or endogenous receptors and can be applied to primary cells.
The AlphaLISA® SureFire® Ultra™ Multiplex phospho-Rb (Ser780) + Total Rb assay kit is used to measure both the phosphorylation of Rb and total levels of endogenous Rb in cellular lysates. The assay is an ideal system for the screening of modulators of receptor activation (e.g. agonists and antagonists) as well as agents acting intracellularly, such as small molecule inhibitors of signal transduction. The assay will measure Rb phosphorylation by either recombinant or endogenous receptors and can be applied to primary cells.
Measure binding of small molecule drug candidates to target protein in a cellular environment with Alpha SureFire® CETSA® target engagement assays. For use in combination with Pelago Bioscience's CETSA® (Cellular Thermal Shift Assay) technology, this kit provides a convenient no-wash assay for detection and quantitation of small molecule binding to STING, and can be used in hit identification, hit confirmation, and lead optimization studies for increased confidence and better prediction early in the drug discovery process. Please note that a valid CETSA® subscription from Pelago Biosciences is required for use.
The AlphaLISA® SureFire® Ultra™ p-SLP76 (Tyr145) assay is a sandwich immunoassay for quantitative detection of phospho-SLP76 (phosphorylated on Tyr145) in cellular lysates using Alpha Technology.
The AlphaLISA® SureFire® Ultra™ p-SLP76 (Tyr113) assay is a sandwich immunoassay for quantitative detection of phospho-SLP76 (phosphorylated on Tyr113) in cellular lysates using Alpha Technology.
The AlphaLISA® SureFire® Ultra™ total ribosomal protein S6 (RPS6) assay is a sandwich immunoassay for quantitative detection of Ribosomal S6 (phosphorylated and non-phosphorylated) in cellular lysates using Alpha Technology. This assay is intended to be a normalization phosphorylation studies.
This kit has been pre-validated for use in combination with Pelago Bioscience’s CETSA® (Cellular Thermal Shift Assay) technology. Please note that further assay optimization will be required in order to adapt the kit to your particular cell line and experimental conditions. A valid CETSA® licence from Pelago Bioscience or a single kit agreement is required for using the CETSA® technology.
The AlphaLISA® SureFire® Ultra™ p-Ribosomal Protein S6 (Ser235/236) assay is a sandwich immunoassay for quantitative detection of phospho- Ribosomal Protein S6 (phosphorylated on Ser3235/236) in cellular lysates using Alpha Technology.
The AlphaLISA® SureFire® Ultra™ total RIPK1 assay is a sandwich immunoassay for quantitative detection of RIPK1 (phosphorylated and non-phosphorylated) in cellular lysates using Alpha Technology. This assay is intended to be a normalization phosphorylation studies.
This kit has been pre-validated for use in combination with Pelago Bioscience’s CETSA® (Cellular Thermal Shift Assay) technology. Please note that further assay optimization will be required in order to adapt the kit to your particular cell line and experimental conditions. A valid CETSA® licence from Pelago Bioscience or a single kit agreement is required for using the CETSA® technology.
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