Protein kinases are key focus targets in drug discovery. Kinases regulate most cellular pathways and are responsible for the modification of nearly a third of all human proteins. Due to their substantial involvement in signaling within and between cells, protein kinases have become the second most widely studied group of potential drug targets, after G-protein-coupled receptors (GPCR).
It has been shown deregulation of kinase activity is a frequent cause of disease, particularly cancer. Furthermore, nearly half of identified kinases have not been fully characterized. 爱游戏平台注册登录 provides the tools for all your protein kinase research needs.