Our LANCE® and LANCE® Ultra TR-FRET technologies provide a simple, highly-sensitive, and highly-reproducible platform for detection, quantitation and screening in microplate format. From biomarker detection assays, to cAMP/GPCR studies, to kinase and epigenetic assays, LANCE provides a flexible platform for many applications.
Advantages:
- Time-resolved measurement for clearer signal resolution
- Homogeneous (no wash steps, no separation steps)
- Robust sensitivity
- Long signal stability
- Highly reproducible result
LANCE europium chelates have been optimized for assay performance, signal level, energy transfer efficiency, background and sensitivity of the assay to interferences. The results are a superior S:B ratio and a very sensitive TR-FRET assay. You use less label and get more efficient use of assay reagents.
Our small (<800 Da) ULight acceptor dye decreases steric hindrance while maximizing signal for labeled substrates. The SureLight® APC acceptor dye provides a broad, antenna-like structure to help align fluorophores for optimal TR-FRET signal, making it excellent for measuring large binding interactions.
