Genhance on the ASK
Overview
Genhance™ agents are small molecule fluorescent agents that can be used as a control or in vascular permeability imaging/blood pooling. Genhance enables imaging of circulation, blood vessels, and the vasculature. It is typically imaged using intravital microscopy (IVM). Genhance™ 680 is the acid form of VivoTag® 680 and Genhance™ 750 is the acid form of VivoTag® 750. Both agents come in two sizes (1 mg and 5 mg).
Products and catalog numbers
| Product | Catalog Number | Ex/Em wavelength (nm) | Molecular weight (g/mol) | Validated Experiments | Applications | Storage and Stability |
|---|---|---|---|---|---|---|
| Genhance 680
(1 mg) | NEV10117 | 670/688 | ~ 1646 | In vivo | Control
Vascular | Technical Data Sheet |
| Genhance 680
(5 mg) | NEV10130 | 670/688 | ~ 1646 | In vivo | Control
Vascular | Technical Data Sheet |
| Genhance 750
(1 mg) | NEV10118 | 750/775 | 1086 | In vivo | Control
Vascular | Technical Data Sheet |
| Genhance 750
(5 mg) | NEV10177 | 750/775 | 1086 | In vivo | Control
Vascular | Technical Data Sheet |
Using Genhance in vivo
| Genhance | Route of Injection | Mouse Dose (25 g) | Rat Dose (250 g) | Blood t 1/2 | Tissue t 1/2 | Optimal imaging time | Optimal Re-injection Time (complete clearance) | Route of Metabolism/ background tissue | FMT& IVIS settings |
|---|---|---|---|---|---|---|---|---|---|
| Genhance 680 | IV | 50 ug | 150-500 ug | 0.5 h | not determined | 0.5 h | not determined | Bladder | FMT 680/700
IVIS 675/720 |
| Genhance 750 | IV | 50 ug | 150-500 ug | 0.5 h | not determined | 0.5 h | not determined | Bladder | FMT 750/770
IVIS 745/800 |
Citations
Please visit our Citations Library for references using Genhance on the IVIS or on the FMT.
- Application Support Knowledge Base Home
- In Vivo and Preclinical Imaging
- Acute inflammation preclinical and in vivo imaging
- Angiogenesis on the ASK
- Arthritis on the ASK
- Atherosclerosis on the ASK
- Bacterial Infection on the ASK
- Bone biology and preclinical imaging
- Oncology on the ASK
- Pulmonary inflammation and preclinical imaging
- Vascular disease on the ASK
- Bioluminescent Cell Lines
- Light-producing microbes on the ASK
- RediFect lentiviral particles for in vivo and ex vivo imaging
- Luciferin and Coelenterazine Substrates
- Activatable imaging agents on the ASK
- Targeted in vivo agents on the ASK
- Vascular in vivo agents on the ASK
- AngioSense on the ASK
- AngioSPARK on the ASK
- Annexin Vivo on ASK
- Bacterial Detection Probe on the ASK
- BacteriSense on the ASK
- BombesinRSense on the ASK
- CAT B FAST on the ASK
- CAT K FAST on the ASK
- COX-2 probe on the ASK
- FolateRSense on the ASK
- GastroSense on the ASK
- Genhance on the ASK
- GFR-Vivo on the ASK
- HypoxiSense on the ASK
- IntegriSense on the ASK
- MMPSense on the ASK
- Neutrophil Elastase on the ASK
- OsteoSense on the ASK
- ProSense on the ASK
- PSA FAST on the ASK
- Rediject 2-DG on the ASK
- ReninSense on the ASK
- Superhance on the ASK
- TLectinSense on the ASK
- Transferrin-Vivo 750 on the ASK
- VivoTag on the ASK
- Depilation on the ASK
- IP injections for NIRF agents on ASK
- Lateral tail vein injections on the ASK
- Radioimaging on the ASK