In this white paper, we will introduce the concept of Single Cell ICP-MS (SC-ICP-MS), where individual cells are rapidly analyzed for metal content.
Research into the effectiveness of anti-cancer medications is explored by monitoring the uptake rate of cisplatin at the cellular level, advancing the knowledge of cellular interactions with metal-containing species. SC-ICP-MS allows users to monitor metal content within single cells for intrinsic metal content, uptake of ionic and/or nanoparticulate contaminants, handle lower cell numbers compared to conventional methods, and use minimal sample preparation.