Label-Free Analysis of Cardiomyocyte Beating using the Opera Phenix Plus System

Drug-induced cardiotoxicity is a frequent cause of drug attrition during drug development and can lead to the withdrawal of drugs from the market, so non-invasive approaches that allow quick and reliable assessment of the cardiotoxic potential of a compound are key to improve drug safety.

In this application note, learn how the Opera Phenix^® Plus high-content screening system together with the MuviCyte^™ live-cell imaging system can be used for:

• Reliable quantification of cardiomyocyte beating frequency
• Fast frame rate imaging up to 100 fps to accurately capture fast cellular responses
• Tip-based on-board pipetting compatible with 96 and 384-well plates
• Stable environmental conditions with temperature, CO2, and humidity control