For research use only; not for diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).
Histone Deacetylase 5 (HDAC5) is an enzyme and class II HDAC responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation indicates epigenetic repression and is involved in transcriptional regulation, cell cycle progression, and developmental events. Mutations in HDAC expression are strongly associated with loss of tumor protection genes. HDAC mutations are associated with breast cancer, hepatocellular carcinoma (HCC), lung cancer, pancreatic neuroendocrine cancer, and colorectal cancer.
The AlphaLISA SureFire Human and Mouse Phospho-HDAC5 (Ser259) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-HDAC5 (Ser259) in cellular lysates, using Alpha Technology.
檢測目標 | HDAC5 |
---|---|
檢測技術 | Alpha |
自動化兼容 | Yes |
檢測方法 | Alpha |
實驗類型 | In vitro |
產品品牌名稱 | AlphaLISA SureFire Ultra |
運輸條件 | 藍冰 |
Target Species | Human, Mouse |
治療領域 | Oncology |
產品尺寸 | 10,000 Assay Points |
Find out about our range of integrated solutions for drug discovery screening in this e-brochure.
Our screening solutions for high-throughput screening, phenotypic screening and data analysis help to streamline drug discovery workflows in labs across the globe. Our portfolio includes automat ...
Product brochure for the Alpha Technology, a versatile, no wash, homogeneous assay technology that's suitable for a broad range of applications.
The introduction of enzyme-linked immunosorbent assays (ELISAs) in the early 1970’s offered researchers a non-radiometric immunoassay platform without compromising sensitivity. Over the last 50 years scientists have made huge strides in disease research and drug discovery and a demand for greater ...