For research use only; not for diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).
Leucine-rich repeat kinase 2 (LRRK2, Dardarin, or PARK8) is a large, multifunctional kinase enzyme, classified as a member of the ROCO superfamily. The ROCO family is characterized by the presence of tandem Ras of complex (Roc) G-domain, kinase domains, and carboxy- terminal of Roc (COR) sequence which links them. LRRK2 plays a role in lysosomal function and the innate immunity in the brain (microglia activation) and modulates Tau phosphorylation via GSK-3b. Mutations in LRRK2 are associated with Parkinson’s disease.
The AlphaLISA SureFire Human and Mouse Total LRRK2 Detection Kit is a sandwich immunoassay for the quantitative detection of total LRRK2 in cellular lysates, using Alpha Technology.
檢測目標 | LRRK2 |
---|---|
檢測技術 | Alpha |
自動化兼容 | Yes |
檢測方法 | Alpha |
實驗類型 | In vitro |
產品品牌名稱 | AlphaLISA SureFire Ultra |
運輸條件 | 藍冰 |
Target Species | Human, Mouse |
治療領域 | Neuroscience |
產品尺寸 | 500 Assay Points |
Find out about our range of integrated solutions for drug discovery screening in this e-brochure.
Our screening solutions for high-throughput screening, phenotypic screening and data analysis help to streamline drug discovery workflows in labs across the globe. Our portfolio includes automat ...
Product brochure for the Alpha Technology, a versatile, no wash, homogeneous assay technology that's suitable for a broad range of applications.
The introduction of enzyme-linked immunosorbent assays (ELISAs) in the early 1970’s offered researchers a non-radiometric immunoassay platform without compromising sensitivity. Over the last 50 years scientists have made huge strides in disease research and drug discovery and a demand for greater ...