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AlphaLISA SureFire Ultra Human and Mouse Total LRRK2 Detection Kit, 50,000 Assay Points

The AlphaLISA® SureFire® Ultra Human and Mouse Total LRRK2 assay is a sandwich immunoassay for quantitative detection of total LRRK2 in cellular lysates using Alpha Technology.

For research use only; not for diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).

Part Number
Unit Size
List Price
Your Price
Quantity
ALSU-TLRRK2-A500
500 Assay Points
2236.00 USD
 
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ALSU-TLRRK2-A10K
10,000 Assay Points
13600.00 USD
 
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ALSU-TLRRK2-A50K
50,000 Assay Points
43900.00 USD
 
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ALSU-TLRRK2-A-HV
100 Assay Points
662.00 USD
 
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Overview

Leucine-rich repeat kinase 2 (LRRK2, Dardarin, or PARK8) is a large, multifunctional kinase enzyme, classified as a member of the ROCO superfamily. The ROCO family is characterized by the presence of tandem Ras of complex (Roc) G-domain, kinase domains, and carboxy- terminal of Roc (COR) sequence which links them. LRRK2 plays a role in lysosomal function and the innate immunity in the brain (microglia activation) and modulates Tau phosphorylation via GSK-3b. Mutations in LRRK2 are associated with Parkinson’s disease.

The AlphaLISA SureFire Human and Mouse Total LRRK2 Detection Kit is a sandwich immunoassay for the quantitative detection of total LRRK2 in cellular lysates, using Alpha Technology.

Formats

  • The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.
  • The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.
  • The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.
  • The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.

AlphaLISA SureFire Ultra kits are compatible with

  • Cell and tissue lysates
  • Antibody modulators
  • Biotherapeutic antibodies

Alpha SureFire kits can be used for

  • Cellular kinase assays
  • Receptor activation studies
  • Screening

Specifications

Assay Target LRRK2
Assay Technology Alpha
Automation Compatible Yes
Detection Method Alpha
Experimental Type In vitro
Product Brand Name AlphaLISA SureFire Ultra
Shipping Condition Blue Ice
Target Species Human, Mouse
Therapeutic Area Neuroscience
Unit Size 50,000 Assay Points
Resources, Events & More
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Application Brief

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Brochure

Alpha Technology Solutions

Product brochure for the Alpha Technology, a versatile, no wash, homogeneous assay technology that's suitable for a broad range of applications.

PDF 2 MB
Drug Discovery Screening Solutions Brochure

Find out about our range of integrated solutions for drug discovery screening in this e-brochure.

Our screening solutions for high-throughput screening, phenotypic screening and data analysis help to streamline drug discovery workflows in labs across the globe. Our portfolio includes automat ...

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