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AlphaLISA SureFire Ultra Human Phospho-VAV1 (Tyr174) Detection Kit, 10,000 Assay Points

The AlphaLISA® SureFire® Ultra Human Phospho-VAV1 (Tyr174) assay is a sandwich immunoassay for quantitative detection of phospho-VAV1 (Tyr174) in cellular lysates using Alpha Technology.

For research use only; not for diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).

貨號
產品尺寸
ALSU-PVAV1-A500
500 Assay Points
更多
ALSU-PVAV1-A10K
10,000 Assay Points
更多
ALSU-PVAV1-A50K
50,000 Assay Points
更多
ALSU-PVAV1-A-HV
100 Assay Points
更多
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詳細信息

VAV1 is a Rho-family guanine nucleotide exchange factor that is encoded by a proto-oncogene, Vav Guanine Nucleotide Exchange factor 1. Wild-type VAV1 is recognized as a cardinal signal transducer protein in the hematopoietic system, where it is exclusively expressed. However, mutations in various domains of the VAV1 protein are present in human cancers, including T-cell leukemia/lymphoma, peripheral T-cell lymphomas, lung adenocarcinoma, and squamous cell carcinomas. VAV1 is also an activator of T and B cell receptor signaling, therefore making it a potential target for protein degradation therapies to combat autoimmune disease, such as multiple sclerosis.

The AlphaLISA SureFire Human Phospho-VAV1 (Tyr174) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-VAV1 (Tyr174) in cellular lysates, using Alpha Technology.

Formats

  • The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.
  • The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.
  • The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.
  • The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.

AlphaLISA SureFire Ultra kits are compatible with

  • Cell and tissue lysates
  • Antibody modulators
  • Biotherapeutic antibodies

Alpha SureFire kits can be used for

  • Cellular kinase assays
  • Receptor activation studies
  • Screening

規格

檢測目標 VAV1
檢測技術 Alpha
自動化兼容 Yes
檢測方法 Alpha
實驗類型 In vitro
產品品牌名稱 AlphaLISA SureFire Ultra
運輸條件 藍冰
Target Species Human
治療領域 Oncology, Immuno-oncology
產品尺寸 10,000 Assay Points
資源
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產品手冊

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應用簡報

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