A modified cellulose including the combination of 3-chloro-4-methylphenylcarbamate and 3,5-dichlorophenylcarbamate bonding groups coated on high purity, high performance spherical silica particles. This combination of bonded groups stabilizes the solubility of coated phase making for a durable phase similar to other widely used coated phases. The use of cellulose modified with chlorinated phenyl groups provides for the separation for many previously unresolved/poorly resolved chiral mixtures by providing unique separation characteristics.
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Chirality has become critically important in the pharmaceutical, chemical, and agricultural industries. The subtle differences that make compounds chiral can produce dramatically different pharmacological effects in biological systems. As a result, the demand for stereoselective separation techniques and analytical assays to evaluate the enantiomeric purity of chiral compounds, has increased. Chiral chromatography in the forms of HPLC and SFC has become a necessary tool - not only for the analytical determination of enantiomeric purity, but also for the isolation and purification of enantiomers.
As a leader in chiral separations we are able to offer you a broad range of ES Industries ChromegaChiral™ Chiral Stationary Phases (CSPs) for your analytical and preparative chromatography needs. Existing chiral stationary phases can separate a wide variety of chiral mixtures, however there are still enantiomeric mixtures that are difficult to separate limiting their characterization. This provides our drive to develop new CSPs with differing chiral selectivities.
| Inner Diameter | 4.6 mm |
|---|---|
| Length | 150.0 mm |
| Particle Size | 5.0 µm |
| Phase | CCC |
Today's advanced and increasingly diverse laboratories are facing new challenges on a daily basis – starting from raw materials quality through to the finished product. Our comprehensive portfolio of analytical solutions, combined with quality consumables, is designed to give you higher accuracy, ...
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ES Industries is known for its innovative and highly efficient HPLC and supercritical fluid chromatography (SFC) column chemistries. The team has over 40 years ...
Selecting the right HPLC Column for your analysis can make all the difference. There are many considerations when selecting columns, like the molecular weight of your target analytes, their solubility characteristics, and their interactions with stationary phase chemistries.
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