ChromegaChiral™ CCX is a modified amylose coated on high purity, high performance spherical silica particles. The chemical modification includes the combination of chemical bonding groups of methylbenzylcarbamate and 3,5-dimethylphenylcarbamate attached to amylose. This combination of bonded groups stabilizes the solubility of coated phase, making for a durable phase similar to other widely used coated phases. The use of amylose modified with phenyl groups moiety provides for the separation for many previously unresolved/poorly resolved chiral mixtures. This chemical modification provides for unique separation behaviour.
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Chirality has become critically important in the pharmaceutical, chemical, and agricultural industries. The subtle differences that make compounds chiral can produce dramatically different pharmacological effects in biological systems. As a result, the demand for stereoselective separation techniques and analytical assays to evaluate the enantiomeric purity of chiral compounds, has increased. Chiral chromatography in the forms of HPLC and SFC has become a necessary tool - not only for the analytical determination of enantiomeric purity, but also for the isolation and purification of enantiomers.
As a leader in chiral separations we are able to offer you a broad range of ES Industries ChromegaChiral Chiral Stationary Phases (CSPs) for your analytical and preparative chromatography needs. Existing chiral stationary phases can separate a wide variety of chiral mixtures, however there are still enantiomeric mixtures that are difficult to separate limiting their characterization. This provides our drive to develop new CSPs with differing chiral selectivities.
| Inner Diameter | 4.6 mm |
|---|---|
| Length | 50.0 mm |
| Particle Size | 3.0 µm |
| Phase | CCX |
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