Stable, recombinant ValiScreen® cell line expressing the Chemokine receptor CCR1, human recombinant in CHO-K1 host cells.
false falseCell Line Terms and Conditions must be accepted before orders are placed. Additional agreement needed for commercial use.
爱游戏平台注册登录 ’s ValiScreen® cell lines are provided in two vials of frozen cells, each containing ∽2.5 x 106 cells. Detailed product information as well as recommended cell culture conditions and validation assay date are available for each cell line.
Clonal selection for 爱游戏平台注册登录 ’s ValiScreen cell lines is carried out with receptor binding. High and low expressors are then tested and selected for optimal binding and functional response according to the receptor specific transduction pathway.
爱游戏平台注册登录 ’s ValiScreen cell lines require accepted cell line Terms and Conditions prior to order processing. Additional agreement needed for commercial use. Contact us using the Request More Information button above for additional information regarding required documentation.
檢測目標類 | GPCR |
---|---|
檢測目標類型 | Cell line |
檢測驗證 | Binding, cAMP |
G-Alpha天然受體 | Gi/Go |
宿主細胞 | CHO-K1 |
產品品牌名稱 | ValiScreen |
受體類型 | Chemokine |
第二信使釋放 | cAMP |
運輸條件 | 幹冰 |
特殊訂購信息 | Requires accepted Terms and Conditions. Additional agreement needed for commercial use. |
治療領域 | Inflammation |
產品尺寸 | 5 million cells |
爱游戏平台注册登录 ’s validated, ready-to-use AequoZen™or cAMPZen™ frozen, irradiated cells make it easier for you to perform functional testing of GPCRs. Just thaw and use! Reliable, convenient AequoZen cells for aequorin calcium testing or cAMPZen cells for cAMP testing let you get the testing done. So yo ...
Discover a comprehensive collection of GPCR cell lines, membrane preparations, and complementary radioligands designed to drive your GPCR research. Utilize this selection guide to easily identify:
Aequorin and Photina cell lines – the alternative calcium flux assay. PDL-coated microplates improve your performance
Aequorin-based Ca2+ assays represent a new paradigm in drug discovery research for cell-based assays for Ca2+-coupled GPCRs and ion channels. In the aequorin assay, cells co-expressing apoaequorin and the target receptor are first incubated with the co-factor coelenterazinein order to reconstitute t ...
Aequorin is a photo protein originating from the jellyfish Aequorea Victoria. The apo-enzyme (apoaequorin) is a 21 kD protein, which requires a hydrophobic prosthetic group, coelenterazine, to be converted to aequorin,the active form of the enzyme. This enzyme possesses 3 calcium binding sites which ...