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Human IL12/IL12Rβ1 binding kit, 10000 Tests

The Human IL12/IL12Rβ1 binding kit is designed to identify human IL12/IL12Rβ1 inhibitors.

貨號 64BDIL12PEH
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詳細信息

Also known as NKSF (natural killer cell stimulatory factor) and CLMF (cytotoxic lymphocyte maturation factor), IL12 is produced by macrophages and B cells. Along with IFN gamma, IL12 promotes the differentiation of naïve T cells into TH1 cells, which in turn release IFNg and IL2. Because of its effects on TH1 induction, IL12 is strongly linked to autoimmunity. IL12 is a heterodimer of p35 and p40 which binds the heterodimeric IL12Rβ1, IL12Rβ2 complex.

The Human IL12/IL12Rβ1R assay is highly specific for IL12/IL12Rβ1 and hence is especially suitable for the discovery and characterization of anti p40 antibodies.

規格

檢測目標類型 Kit
檢測技術 HTRF
數量 1.0
保質期 90 day(s)
運輸條件 幹冰
治療領域 Inflammation
產品尺寸 10000 Tests
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