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Phospho-Rb (Ser780) Cellular Kit, 500 Tests

This HTRF kit enables the cell-based quantitative detection of phosphorylated Rb as a readout of the G0/G1 cell phase transition.

貨號 64RBS780PEG
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詳細信息

This HTRF cell-based assay conveniently and accurately quantifies phosphorylated Retinoblastoma protein at Ser780. Rb belongs to the pocket protein family and acts as a tumor suppressor, regulating cell cycle progression. The active underphosphorylated Rb form interacts and represses the transcriptional activity of E2F factors, thereby preventing G0/G1 cell cycle transition and progression in the cell cycle. In the presence of mitogenic signals, cyclin D-CDK4/6, followed by cyclin E-CDK2, sequentially phosphorylate and inactivate Rb, releasing the E2F transcription factors required for cell cycle progression.

規格

檢測目標類型 Kit
檢測技術 HTRF
數量 1.0
保質期 90 day(s)
運輸條件 幹冰
治療領域 Oncology & Inflammation
產品尺寸 500 Tests
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