The Phospho-SMAD2 (Ser465/467) kit enables the cell-based quantitative detection of SMAD2 phosphorylated on Ser465/467, as a readout of the TGFb pathway.
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This HTRF cell-based assay enables the rapid, quantitative detection of SMAD2 phosphorylated at Serine 465/467, as a readout of TGF-ß signaling activity.
TGF-ß receptors directly activate SMAD2 by phosphorylation at Ser465/467, causing it to translocate to the nucleus and regulate gene expression involved in apoptosis, migration, and differentiation, as well as in immune/inflammatory responses and extracellular matrix remodeling.
| 檢測目標類型 | Kit |
|---|---|
| 檢測技術 | HTRF |
| 數量 | 1.0 |
| 保質期 | 90 day(s) |
| 運輸條件 | 幹冰 |
| 治療領域 | NASH/Fibrosis, Cardiovascular, Oncology & Inflammation, Metabolism/Diabetes |
| 產品尺寸 | 50000 Tests |
