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IVISbrite Staphylococcus aureus Xen36 Bioluminescent Bacterial Strain

IVISbrite Staphylococcus aureus Xen36 bioluminescent bacteria was derived from a parental strain from the American Type Culture Collection (ATCC), used under license. For in vitro or in vivo imaging applications, IVISbrite S. aureus-Xen36 possesses a stable copy of the Photorhabdus luminescens lux operon on the native plasmid.

For research use only. Not for use in diagnostic procedures.

貨號 119243
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詳細信息

Infectious disease is a perennially important area for both life science research and drug discovery. Some of the first applications of IVIS® imaging technology were in tracking infections and monitoring host responses, and these applications are still at the forefront of research. Our bioluminescent infectious disease light-producing microorganisms have been developed to mimic both acute and chronic standard infection protocols presently used by researchers.

  • Engineered Bacterium: Staphylococcus aureus - Xen36
  • Parental Strain: American Type Culture Collection, used under license
  • In Vitro/Ex Vivo: Growth, Biochemical, and Antibiogram profiles, Catheter model
  • In Vivo: Biofilm

Advantages of using bioluminescent light-producing microorganisms for drug discovery in vitro:

  • Rapid and readily amenable to high throughput screening, e.g., 96 or 384-well format
  • Sensitivity - subtle changes in cellular viability are rapidly detected
  • Inexpensive - no additional substrates needed for bacterial assays

 

Advantages of using bioluminescent light-producing microorganisms for drug discovery in vivo:

  • Rapid identification of lead drug candidates
  • Real-time efficacy data
  • May help to decrease drug failure by allowing disease relapse to be monitored in the same animal

規格

革蘭氏陽性革蘭氏陰性 Gram positive
熒光素酶分類 Bacterial luciferase
光學成像分類 Bioluminescence Imaging
產品品牌名稱 IVISbrite
運輸條件 環境
治療領域 Infectious Diseases
產品尺寸 1 agar plate
資源
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Ebook

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產品手冊

In Vivo Imaging Reagents

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指南

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白皮書

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The primary goal of preclinical imaging is to improve the odds of clinical success and reduce drug discovery and development time and costs. Advances in non-invasive in vivo imaging techniques have raised the use of animal models in drug discovery and development to a new level by enabling quick ...

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