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IVISense MMP 680 Fluorescent Probe (MMPSense) | 爱游戏平台注册登录
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IVISense MMP 680 Fluorescent Probe (MMPSense)

Matrix metalloproteinases (MMPs) are calcium-dependent zinc containing endopeptidases responsible for the degradation of most of extracellular matrix proteins during organogenesis, growth and normal tissue turnover. MMPs play a role in almost every biological cell process from embryo implantation to cell death and have been implicated in a wide range of diseases including inflammation, arthritis, pulmonary disease, cancer and more.

爱游戏平台注册登录 ’s IVISense MMP NIR activatable fluorescence probes (MMPSense®) are designed to evaluate many disease related processes including cancer progression, rheumatoid arthritis, pulmonary disease and more as well as evaluating therapeutic efficacy of potential drug candidates.

For research use only. Not for use in diagnostic procedures.

Part Number
SKU Display Name
List Price
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NEV10126
IVISense MMP 680 Fluorescent Probe (MMPSense)
653.00 USD
 
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NEV10100
IVISense MMP 645 FAST Fluorescent Probe (MMPSense)
654.00 USD
 
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NEV10168
IVISense MMP 750 FAST Fluorescent Probe (MMPSense)
653.00 USD
 
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Overview

IVISense MMP 680 is excited by 680 + 10 nm excitation light, and emits at 700 + 10 nm. MMP 680 has an optimal imaging window of 24-36 hours after injection, allowing workflow flexibility in acquiring data in large animal cohorts. Including IVISense MMP 680 in careful experimental design allows for multiplexing with other channels and/or imaging times, and so can be paired with other probes to achieve maximum efficiency and flexibility in imaging.

Specifications

Fluorescent Agent Type Activatable
Optical Imaging Classification Fluorescence Imaging
Product Brand Name IVISense
Quantity in a Package Amount 1.0 Units
Shipping Condition Blue Ice
Therapeutic Area Atherosclerosis, Arthritis, Inflammation, Oncology/Cancer
Unit Size 1 Vial (10 doses)
Wave Length 680 nm
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Application Note

Multiplex 2D Imaging of NIR Molecular Imaging Agents on the IVIS SpectrumCT and FMT 4000

Epifluorescence (2D) imaging of superficially implanted mouse tumor xenograft models offers a fast and simple method for assessing tumor progression or response to therapy. This approach for tumor assessment requires the use of near infrared (NIR) imaging agents specific for different aspects of tum ...

PDF 4 MB

Brochure

In Vivo Imaging Reagents

Our comprehensive range of bioluminescent and fluorescent imaging reagents provide researchers with the necessary tools to better understand early disease-related biological changes, track disease progression, help guide the drug discovery process, and evaluate efficacy and safety of drug candida ...

PDF 1 MB

Data Sheet

MMPSense 680 (Protocol)

MMPSense 680 Activatable Fluorescent Imaging Agent

PDF 256 KB

Ebook

In Vivo Imaging Solutions eBook

Researchers trust our in vivo imaging solutions to give them reliable, calibrated data that reveals pathway characterization and therapeutic efficacies for a broad range of indications. Our reagents, instruments, and applications support have helped hundreds of research projects over the years. And ...

PDF 4 MB

Flyer

Best Practices for Designing An Effective In Vivo Fluorescence Imaging Study

Fluorescence molecular imaging is the visualization of cellular and biological function in vivo to gain deeper insights into disease processes and treatment effects. Designing an effective study from the beginning can help save time and resources.

Learn about several important best p ...

PDF 507 KB

Guide

IVISense™ Fluorescent Probe Selector Guide for Oncology Research

The goal of in vivo fluorescence molecular imaging is to enable non-invasive visualization and quantification of cellular and biological functioning to better understand and characterize disease processes and treatment effects earlier within the context of a biological system.

This s ...

PDF 4 MB

White Paper

The Role of In Vivo Imaging in Drug Discovery and Development

The primary goal of preclinical imaging is to improve the odds of clinical success and reduce drug discovery and development time and costs. Advances in non-invasive in vivo imaging techniques have raised the use of animal models in drug discovery and development to a new level by enabling quick ...

PDF 547 KB
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