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IVISense Osteo 680 Fluorescent Probe (OsteoSense)

Image and quantify osteoporosis, arthritis, cancer metastases, and other bone diseases, as well as normal bone growth and resorption, in vivo with IVISSense Osteo Fluorescent Imaging probes (OsteoSense). As opposed to other imaging modalities such as CT or x-ray which raise the risk of harmful irradiation to the subject, in vivo fluorescence imaging offers no radiation exposure concerns, and when performed with optimized hydroxyapatite-targeted probes such as IVISense Osteo, can image and quantify bone growth and elucidate the biology of bone remodeling.

IVISense Osteo probes are available in 3 wavelengths: 680, 750, and 800.

For research use only. Not for use in diagnostic procedures.

貨號
SKU顯示名稱
NEV10020EX
IVISense Osteo 680 Fluorescent Probe (OsteoSense)
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NEV10053EX
IVISense Osteo 750 Fluorescent Probe (OsteoSense)
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NEV11105
IVISense Osteo 800 Fluorescent Probe (OsteoSense)
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詳細信息

IVISense Osteo NIR fluorescent bisphosphonate imaging probes are designed to bind with high affinity to hydroxyapatite (HA) both in vivo and in vitro. Since HA is known to bind pyrophosphonates and phosphonates as well as synthetic bisphosphonates with high affinity, IVISense Osteo agents offer a safe and easy way to assess the subtle bone mineral changes that occur in bone growth, bone loss, and in diseases that damage bone, using subtherapeutic doses for imaging.

IVISense Osteo 680 is excited by 668 ± 10 mn excitation light and emits at 687 ± 10 mn. Including IVISense Isteo 680 in careful experimental design allows for multiplexing with other channels and/or imaging times, and so can be paired with other probes to achieve maximum efficiency and flexibility in imaging.

規格

熒光劑類型 Targeted
光學成像分類 Fluorescence Imaging
產品品牌名稱 IVISense
包裝量 1.0 Units
運輸條件 環境
治療領域 Atherosclerosis, Arthritis, Oncology/Cancer
產品尺寸 1 Vial (10 doses)
波長 680 nm
資源
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Ebook

了解更多請點擊下載小動物活體成像解決方案

Researchers trust our in vivo imaging solutions to give them reliable, calibrated data that reveals pathway characterization and therapeutic efficacies for a broad range of indications. Our reagents, instruments, and applications support have helped hundreds of research projects over the years. And ...

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產品手冊

In Vivo Imaging Reagents

Our comprehensive range of bioluminescent and fluorescent imaging reagents provide researchers with the necessary tools to better understand early disease-related biological changes, track disease progression, help guide the drug discovery process, and evaluate efficacy and safety of drug candida ...

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單頁

Best Practices for Designing An Effective In Vivo Fluorescence Imaging Study

Fluorescence molecular imaging is the visualization of cellular and biological function in vivo to gain deeper insights into disease processes and treatment effects. Designing an effective study from the beginning can help save time and resources.

Learn about several important best p ...

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技術說明

OsteoSense 680 EX (Protocol)

OsteoSense 680 EX in vivo fluorescent imaging agent protocol

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指南

IVISense™ Fluorescent Probe Selector Guide for Oncology Research

The goal of in vivo fluorescence molecular imaging is to enable non-invasive visualization and quantification of cellular and biological functioning to better understand and characterize disease processes and treatment effects earlier within the context of a biological system.

This s ...

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海報

Imaging of Cathepsin K activity in rodent models of bone turnover and soft tissue calcification

Imaging of Cathepsin K activity in rodent models of bone turnover and soft tissue calcification

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白皮書

The Role of In Vivo Imaging in Drug Discovery and Development

The primary goal of preclinical imaging is to improve the odds of clinical success and reduce drug discovery and development time and costs. Advances in non-invasive in vivo imaging techniques have raised the use of animal models in drug discovery and development to a new level by enabling quick ...

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