In vivo optical imaging of vascular changes and vascular leak is an emerging modality for studying altered physiology in a variety of different cancers and inflammatory states. In oncology, increases in tumor vascular permeability can be an early indicator of tumor angiogenesis. In inflammatory disease increased vascular permeability can indicate alterations in fluid homeostasis in an acute edema response or in chronic organ conditions.
爱游戏平台注册登录 ’s IVISense™ Vascular NIR fluorescent probes (AngioSense®) are designed to evaluate vascular changes to better understand various disease states or provide valuable information on the effects of drug candidates earlier in the development process.
For research use only. Not for use in diagnostic procedures.
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IVISense Vascular 680 fluorescent imaging probe (AngioSense 680EX) is an in vivo blood pool vascular agent that remains localized in the vasculature for extended periods of time (0-4 hrs) enabling imaging of vascularity, perfusion, and vascular permeability at a wavelength of 680 nm. The probe accumulates in tumors and arthritic joints at 24 hrs. IVISense Vascular 680 fluorescent agent can be used as a single probe or multiplexed with probes at other wavelengths.
| Fluorescent Agent Type | Vascular |
|---|---|
| Optical Imaging Classification | Fluorescence Imaging |
| Product Brand Name | IVISense |
| Quantity in a Package Amount | 1.0 Units |
| Shipping Condition | Blue Ice |
| Therapeutic Area | Vascular disease, Angiogenesis, Arthritis, Inflammation, Oncology/Cancer |
| Unit Size | 1 Vial (10 doses) |
| Wave Length | 680 nm |
Optical-based in vivo imaging of vascular changes and vascular leak is an emerging modality for studying altered physiology in a variety of different cancers and inflammatory states. A number of fluorescent imaging probes that circulate with the blood, but have no target selectivity, have been used ...
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AngioSense 680 EX in vivo imaging agent protocol for preparing mice for imaging, preparing AngioSense 680EX agent, injections of agent into mice, imaging injected mice on IVIS and FMT imaging systems
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