For research use only; not for diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).
Please note control lysates are sold separately, catalog number TRF4026S.
Formats:
LANCE® and LANCE® (Lanthanide chelate excite) Ultra are homogeneous (no wash) TR-FRET (time-resolved fluorescence resonance energy transfer) technologies. One antibody of interest is labeled with a donor fluorophore (a LANCE Europium chelate) and the second antibody is labeled with an acceptor fluorophore [ULight™ dye]. Upon excitation at 320 or 340 nm, energy can be transferred from the donor Europium chelate to the acceptor fluorophore if sufficiently close for FRET (~10 nm). This results in the emission of light at 665 nm. Data are represented as ratiometric (665/615 nm X 10,000).
LCK is a cytoplasmic phosphoprotein from the Src family of non-receptor tyrosine kinases. LCK regulates T cell activation by associating with CD4 and CD8 surface receptors on T cells. Phosphorylation at Y394 enhances kinase activity. LCK is associated with Immunodeficiency 22 and CD45 deficiency. No-death receptor apoptosis is also involves LCK.
檢測目標 | LCK |
---|---|
檢測目標類 | Phosphoprotein |
自動化兼容 | Yes |
檢測方法 | Time-Resolved Fluorescence (TRF), TR-FRET |
產品品牌名稱 | LANCE Ultra |
運輸條件 | 藍冰 |
產品尺寸 | 10,000 Assay Points |
The introduction of enzyme-linked immunosorbent assays (ELISAs) in the early 1970’s offered researchers a non-radiometric immunoassay platform without compromising sensitivity. Over the last 50 years scientists have made huge strides in disease research and drug discovery and a demand for greater ...