We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (B_max), dissociation constants (K_d), association and dissociation rates (k_on and k_off), and inhibitor constants (K_i) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, 爱游戏平台注册登录 has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX315:

1. Sejling, AS., Lange, K.H.W., Frandsen, C.S. et al. (2015), Infrared thermographic assessment of changes in skin temperature during hypoglycaemia in patients with type 1 diabetes, Diabetologia 58: 1898-1906.
2. Dirksen, C., Jørgensen, N.B., Bojsen-Møller, K.N., Kielgast, U., Jacobsen, S.H., Clausen, T.R., Worm, D., Hartmann, B., Rehfeld, J.F., Damgaard, M., Madsen, J.L., Madsbad, S., Holst, J.J., Hansen, D.L. (2013), Gut hormones, early dumping and resting energy expenditure in patients with good and poor weight loss response after Roux-en-Y gastric bypass. Int J Obes, 37 (11): 1452-1459.