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Pancreatic Polypeptide (human), [125I], 50µCi | 爱游戏平台注册登录
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Pancreatic Polypeptide (human), [125I], 50µCi

Human pancreatic polypeptide (PP), labeled with 125I. Pancreatic polypeptide acts as an agonist at Pancreatic polypeptide receptors (Neuropeptide Y receptors), a class of GPCRs involved in appetite, circadian rhythm, and anxiety.

貨號
產品尺寸
NEX315010UC
10 µCi
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NEX315050UC
50 µCi
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詳細信息

We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, 爱游戏平台注册登录 has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX315:

  1. Sejling, AS., Lange, K.H.W., Frandsen, C.S. et al. (2015), Infrared thermographic assessment of changes in skin temperature during hypoglycaemia in patients with type 1 diabetes, Diabetologia 58: 1898-1906.
  2. Dirksen, C., Jørgensen, N.B., Bojsen-Møller, K.N., Kielgast, U., Jacobsen, S.H., Clausen, T.R., Worm, D., Hartmann, B., Rehfeld, J.F., Damgaard, M., Madsen, J.L., Madsbad, S., Holst, J.J., Hansen, D.L. (2013), Gut hormones, early dumping and resting energy expenditure in patients with good and poor weight loss response after Roux-en-Y gastric bypass. Int J Obes, 37 (11): 1452-1459.

規格

檢測方法 Radiometric
新鮮的很多天 Fourth Monday of each month
標簽位置 Nominally Labeled
分子量 4179.0
產品品牌名稱 NEN Radiolabeled Ligands
放射性同位素 I-125
放射性核素 125I
受體類型 Neuropeptide Y
運輸條件 環境
特殊訂購信息 This is a radioactive product - shipping address must have a license to receive radioactive materials.
治療領域 CNS & Neurologic, Metabolic Disorders, Gastrointestinal
產品尺寸 50 µCi
資源
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Using the NENSure Packaging System from 爱游戏平台注册登录

Since 1985, the unique NENSure system has set the standard for radiochemical packaging. Based on proven performance over millions of shipments, the system provides: Ease of use, Safe storage of unused product and Reduced radiation exposure. Many NEN brand research products, including 32P-, 33P-, 35 ...

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