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LabChip GXII Touch HT Protein Characterization System

The LabChip® GXII Touch protein characterization system provides the complete solution for reproducible quantitation, molecular weight sizing and percent purity analysis of protein samples. Leveraging microfluidic electrophoretic separation technology, the LabChip® GXII Touch system enables rapid characterization with minimal sample preparation setup and sample input volume.

Part Number CLS138160
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For research use only. Not for use in diagnostic procedures.

Overview

Versatile instrument for protein analysis and quantitation

  • Multiple assays available for quantification, molecular weight sizing, purity, charge variants and glycan analysis. With our pre-verified assays, there is no (or little) method development needed.
  • Rapidly determine the molecular weight, concentration and purity of every protein within your sample
  • Optimal for all throughput needs, with run cherry-picking to 96-well and 384-well high-throughput compatibility
  • Accelerate design space parameters with protein sample analysis from Quality of Design (QbD) and Design and of Experiment (DoE) studies
  • Instrument is applicable throughout the workflow, whether upstream in R&D through Process Development down to final Quality Control.
  • Intuitive touch screen interface with comprehensive analysis using LabChip® GX software enabling “True high-throughput analytics.” Analyze results electropherogram, tabular and virtual gel formats
The platform supports multiple assays for characterizing proteins in reduced and non-reduced samples including:
  • Analyze critical quality attributes in as few as 42 seconds:
  • Titer (concentration and sizing)
  • Purity assessment
  • Aggregation (covalently linked)
  • Stability (degradation / fragmentation analysis)
  • N-Glycan profiling
  • mAb Charge variant / charge heterogeneity
  • mAb impurity analysis (detect minor impurities)
For research use only. Not for use with diagnostic procedures.

Specifications

21 CFR Part 11 Compatible Yes
Automation Compatible Yes
Depth 49.0 cm
Model Name LabChip GXII Touch HT Protein Characterization System
Product Brand Name LabChip GXII
Research Areas Translational Research
Width 51.0 cm
Resources, Events & More
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Application Brief

LabChip GXII Touch Protein and Nucleic Acid Characterization System

The LabChip® GXII Touch protein and nucleic acid characterization system offers an automated alternative to traditional methods by streamlining slab gel electrophoresis, while also providing the increased throughput and data quality required by biotherapeutics and ...

PDF 2 MB

Application Note

Automated Microfluidic Capillary Electrophoresis for Measurement of Full & Empty Adeno-Associated Virus Capsids

Adeno-associated virus (AAV) particles are intensively being investigated for therapeutic use in gene therapy due to low immunogenicity and ability for long-term gene expression in vivo. Luxturna and Zolgensma are two recently FDA approved drugs that utilize AAV technology for treatment of inheri ...

PDF 1 MB
Characterization of NISTmAb using Protein Clear HR Assay

Enable high-resolution protein purity assessment of monoclonal antibodies w/ Protein Clear HR-assay

PDF 527 KB
Characterization of NISTmAb with Microfluidic CE-SDS using the Protein Clear HR Assay on the LabChip GXII Touch

Capillary electrophoresis (CE), more specifically CE-SDS, is becoming an increasingly popular and routinely used method for monitoring and documenting critical quality attributes for monoclonal antibody therapeutic products, due to its automated operation, on-column detection, great resolving pow ...

PDF 527 KB
LabChip GXII Touch Small RNA Assay

Rapid and automated electrophoresis is an important tool for research and development of new biotherapeutics. The LabChip GXII Touch Biologics Characterization System performs automated microfluidic capillary electrophoresis on reusable chips with analysis times up to 65 seconds per sample. Micro ...

PDF 1 MB
Microcapillary electrophoresis analysis of asymmetrical bispecific antibody products by the ProteinEXact assay using the LabChip GXII Touch

In the area of next-generation antibody therapeutics, bispecific antibodies (bsAb) with their exclusive dual binding functions, predominate in the market. The wide diversity of their formats is only limited by our imagination. Therefore, ensuring quality assessment and characteristic analysis has ...

PDF 1 MB
Microcapillary electrophoresis analysis of asymmetrical bispecific antibody products using the LabChip GXII Touch

In the area of next-generation antibody therapeutics, bispecific antibodies (bsAb) with their exclusive dual binding functions, predominate in the market. The wide diversity of their formats is only limited by our imagination. Therefore, ensuring quality assessment and characteristic analysis has ...

PDF 1 MB

Flyer

Big Impacts From Small RNAs

Our Small RNA assay for the LabChip® GXII Touch Biologics Characterization System provides a fast and easy way to separate and measure a variety of small RNA samples, ranging in size from 20 to 150 nucleotides (nt), including micro RNA (miRNA), small interfering RNA (siRNA) ...

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Guide

Low MW Protein User Guide

User Guide for LabChip GX Touch Protein Low MW assay.

PDF 1 MB
Protein Charge Variant Assay Quick Guide

User Guide for LabChip GXII Touch protein reagents

PDF 95 KB
Protein Charge Variant Assay User Guide

User Guide for LabChip GXII Touch protein reagents

PDF 2 MB
Protein Express Quick Guide

A Protein Express Assay Quick Guide for LabChip GXII Touch and LabChip GXII which includes: Preparing Gel-Dye and Protein Express Chip; Preparing Protein Samples, Ladder and Buffer; Chip Cleaning and Storage; and Assay Specifications.

PDF 162 KB
Protein Express User Guide

The Protocols defined in this User Guide apply to all of the LabChip instrument products running the Protein Express Assay. The LabChip GXII Touch is used for general visual reference in most examples in this guide.

PDF 1 MB

Software Downloads

Software Downloads

Technical Note

Speed Up Your Vaccine Development

The coronavirus, SARS-CoV-2, outbreak has highlighted the need for rapid vaccine development. This complex task requires a high throughput, standardized and reliable screening tool to qualify potential candidates and to ensure quality control.

The automated LabChip® GXII Touc ...

PDF 1 MB

White Paper

Antibody Analysis Using Microfluidic Technology in High Throughput Quality by Design Experiments

Current initiatives in Process Analytical Technology (PAT) and Quality by Design (QbD) are driving the need to identify and thoroughly understand the relation between Critical Process Parameters (CPP) and Critical Quality

Attributes (CQAs)1. Design of Experiment (DOE) studies to test the e ...

PDF 1 MB
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