爱游戏平台注册登录
check quantity

Somatostatin, [125I]Tyr11, 10µCi

Somatostatin, labeled with 125I. Somatostatin binds somatostatin receptors, and inhibits the secretion of insulin and glucagon.

貨號
產品尺寸
NEX389010UC
10 µCi
更多
NEX389050UC
50 µCi
更多
Request Technical Support

請輸入有效數量

請登錄以添加收藏夾。

購物車為空

詳細信息

We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, 爱游戏平台注册登录 has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX389:

  1. Sparre-Ulrich, A.H., Gabe, M.N., Gasbjerg, L.S., Christiansen, C.B., Svendsen, B., Hartmann, B., Holst, J.J., Rosenkilde, M.M. (2017), GIP(3-30)NH2 is a potent competitive antagonist of the GIP receptor and effectively inhibits GIP-mediated insulin, glucagon, and somatostatin release. Biochem Pharmacol, 131: 78-88.
  2. Sparre-Ulrich, A. H., Hansen, L. S., Svendsen, B., Christensen, M., Knop, F. K., Hartmann, B., Holst, J. J., and Rosenkilde, M. M. (2016) Species-specific action of (Pro3)GIP – a full agonist at human GIP receptors, but a partial agonist and competitive antagonist at rat and mouse GIP receptors. British Journal of Pharmacology, 173: 27–38.

規格

檢測方法 Radiometric
新鮮的很多天 Third Monday of each month
標簽位置 Nominally Labeled
產品品牌名稱 NEN Radiolabeled Ligands
放射性同位素 I-125
放射性核素 125I
受體類型 Somatostatin
運輸條件 環境
特殊訂購信息 This is a radioactive product - shipping address must have a license to receive radioactive materials.
治療領域 CNS & Neurologic, Angiogenesis, Pain, Inflammation, Metabolic Disorders
產品尺寸 10 µCi
資源
  • 所有

單頁

Using the NENSure Packaging System from 爱游戏平台注册登录

Since 1985, the unique NENSure system has set the standard for radiochemical packaging. Based on proven performance over millions of shipments, the system provides: Ease of use, Safe storage of unused product and Reduced radiation exposure. Many NEN brand research products, including 32P-, 33P-, 35 ...

PDF 765 KB
Baidu
map