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U-69,593, [Phenyl-3,4-3H]-, 250µCi (9.25MBq)

U-69,593, tritiated at the phenyl-3,4 position. U-69,593 is a selective κ1-opioid receptor agonist.

貨號 NET952250UC
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詳細信息

U-69,593 acts as an agonist at kappa 1 opioid receptors (KORs). These receptors are a class of GPCRs involved in pain, consciousness, stress, and mood.

We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.

Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, 爱游戏平台注册登录 has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NET952:

  1. Meng F, Xie GX, Thompson RC, Mansour A, Goldstein A, Watson SJ, and Akil H (1993) Cloning and pharmacological characterization of a rat kappa opioid receptor. Proc Natl Acad Sci USA 90:9954–9958.

規格

檢測方法 Radiometric
標簽位置 Specifically Labeled
分子量 356.5
產品品牌名稱 NEN Radiochemicals
放射性同位素 H-3
放射性核素 3H
受體類型 Opioid
運輸條件 幹冰
特殊訂購信息 This is a radioactive product - shipping address must have a license to receive radioactive materials.
治療領域 CNS & Neurologic, Pain, Inflammation
產品尺寸 250 µCi
資源
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產品手冊

Radiometric Reagents Guide 2010-2011

For over 50 years 爱游戏平台注册登录 has been a leading supplier of radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments. Today is no different. We have always been committed to providing you products for all of your radiometric needs and we are still committed t ...

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