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LANCE Ultra ULight™-Protein A, 1 nmole

Protein A labeled with ULight™ dye.

For research use only; not for diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).

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產品尺寸
TRF0103-D
1 nmol
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TRF0103-M
10 nmol
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詳細信息

The versatility of LANCE TR-FRET technology allows the assembly of donor and acceptor dye pairs for use in protein binding and other assays. Choose your preferred donor- and acceptor-labeled reagents to design your own assay. This is assay design at its most flexible; featuring the most common affinity biomolecules and europium chelate-labeling reagents. LANCE toolbox reagents can be used to design a variety of assays, including kinase, protein-protein interaction, protein-nucleic acid interaction, protein-small molecule interaction, epigenetic, receptor-ligand binding, nuclear receptor, receptor dimerization, ubiquitination and other post-translational modifications, protease, and other binding and enzymatic assays.

規格

抗體偶聯物 Protein A
檢測目標類 Protein
自動化兼容 Yes
檢測方法 Time-Resolved Fluorescence (TRF), TR-FRET
實驗類型 In vitro
熒光基團 ULight
Format Microplates
產品品牌名稱 LANCE Ultra
運輸條件 幹冰
產品尺寸 1 nmol
資源
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應用文獻

Comparison of LANCE Ultra TR-FRET to 爱游戏平台注册登录 's Classical LANCE TR-FRET Platform for Kinase Applications

Protein kinases play a major role in normal cellular functions such as cell proliferation, angiogenesis, and cell adhesion. Dysregulation of kinase activity has been shown to be associated with several human diseases including cancer, diabetes and morphological disorders. This makes kinases crucial ...

PDF 805 KB
Development and Optimization of Kinase Assays using New LANCE Ultra TR-FRET Reagents

Dysregulation of kinase activity has been shown to be associated with several human diseases including cancer, diabetes and morphological disorders. Because of their function, kinases are crucial targets for drug discovery. Analysis of the human genomehas revealed the existence ofnearly 520 genes en ...

PDF 583 KB

海報

Poster LANCE Ultra Tyrosine kinases

Of the 518 known human kinases, 90 are tyrosine (Tyr) kinases. Protein Tyr kinases play a key role in signal transduction and normal cell growth. They are also involved in numerous proliferative diseases like cancer and atherosclerosis, in addition to a number of autoimmune diseases. For these reaso ...

PDF 276 KB
Novel Substrates for Fluorescence-based Protein Tyrosine Kinase Assays

Protein tyrosine kinases (PTK) are involved in the regulation of many aspects of the cell cycle, including proliferation, differentiation, secretion and apoptosis. Aberrant protein kinase expression or function is a cause or consequence of many human diseases like cancer and atherosclerosis. As a re ...

PDF 276 KB
Comparison of LANCE Ultra with Other TR-FRET Platforms

Protein kinases play a major role in normal cellular functions such as cell proliferation, angiogenesis, and cell adhesion. Dysregulation of kinase activity has been shown to be associated with several human diseases including cancer, diabetes and morphological disorders. This makes kinases crucial ...

PDF 356 KB
Development, Automation and Miniaturization of High-Throughput Serine/Threonine Kinase Assays Using the LANCE® Ultra Platform

Protein kinases are involved in the regulation of many aspects of the cellcycle, including proliferation, differentiation, secretion and apoptosis. Aberrant protein kinase expression or functioning is a cause orconsequence of many human diseases. As a result, kinases have become extremely popular fo ...

PDF 364 KB
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