Stable, recombinant AequoScreen® cell line expressing aequorin and the Melanin-concentrating hormone receptor 1 (MCH1), human recombinant in CHO-K1 host cells.
Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.